Saraswat Istuti, Goel Anjana, Gupta Jyoti
Department of Biotechnology, GLA University, 17km Stone, NH-2 Mathura-Delhi Road Mathura, Chaumuhan, Mathura, Uttar Pradesh, India.
Anticancer Agents Med Chem. 2025;25(1):24-34. doi: 10.2174/0118715206307964240821051756.
, commonly known as the Mexican prickly poppy, has been historically employed in traditional medicine for various ailments, including liver disorders. Given the rising prevalence of liver diseases, including cancer, investigating the potential efficacy of in promoting liver health is of paramount importance. This review aims to provide a comprehensive analysis of the existing literature on the hepatoprotective and anticancer properties of .
A systematic literature search was conducted across PubMed, Google Scholar, and relevant botanical and pharmacological databases. Studies from various sources, including in vitro experiments, animal models, and clinical trials, were included in the review. The search focused on articles published up to 2010-2023, encompassing research that explored the botanical characteristics, chemical composition, traditional uses, and pharmacological properties of , specifically emphasizing its impact on liver health and cancer.
The review revealed a wealth of studies highlighting the diverse pharmacological properties of Argemone mexicana. The botanical composition includes compounds with antioxidant and anti-inflammatory potential, suggesting hepatoprotective effects. Studies using and models demonstrated promising outcomes regarding liver function improvement and inhibition of liver cancer cell proliferation. While some clinical studies supported the traditional uses of , further well-designed trials are warranted to establish its clinical efficacy.
In conclusion, shows promise as a natural agent for promoting liver health and combating liver cancer. Bioactive compounds with antioxidant and anti-inflammatory properties suggest potential hepatoprotective effects. However, translating these findings into clinical practice requires further rigorous investigation, including well-designed clinical trials. This review provides a foundation for future research efforts aimed at elucidating the full therapeutic potential of Argemone mexicana in liver health and cancer management.
蓟罂粟,俗称墨西哥刺罂粟,在传统医学中历史上一直被用于治疗各种疾病,包括肝脏疾病。鉴于包括癌症在内的肝脏疾病患病率不断上升,研究蓟罂粟在促进肝脏健康方面的潜在功效至关重要。本综述旨在对现有关于蓟罂粟肝脏保护和抗癌特性的文献进行全面分析。
在PubMed、谷歌学术以及相关植物学和药理学数据库中进行了系统的文献检索。综述纳入了来自各种来源的研究,包括体外实验、动物模型和临床试验。检索重点是截至2010 - 2023年发表的文章,涵盖探索蓟罂粟植物特征、化学成分、传统用途和药理特性的研究,特别强调其对肝脏健康和癌症的影响。
综述揭示了大量研究突出了蓟罂粟多样的药理特性。其植物成分包括具有抗氧化和抗炎潜力的化合物,表明具有肝脏保护作用。使用细胞和动物模型的研究在改善肝功能和抑制肝癌细胞增殖方面显示出有前景的结果。虽然一些临床研究支持蓟罂粟的传统用途,但仍需要进一步精心设计的试验来确定其临床疗效。
总之,蓟罂粟作为促进肝脏健康和对抗肝癌的天然药物显示出前景。具有抗氧化和抗炎特性的生物活性化合物表明具有潜在的肝脏保护作用。然而,将这些发现转化为临床实践需要进一步严格的研究,包括精心设计的临床试验。本综述为未来旨在阐明蓟罂粟在肝脏健康和癌症管理中的全部治疗潜力的研究工作提供了基础。