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儿童肥胖:肥胖帝国中具有威胁性的“学徒”。

Childhood obesity: The threatening apprentice of the adiposity empire.

作者信息

Zapata J Karina, Gómez-Ambrosi Javier, Frühbeck Gema

机构信息

Department of Endocrinology and Nutrition, Clínica Universidad de Navarra, Pamplona, Spain.

Metabolic Research Laboratory, Clínica Universidad de Navarra, Pamplona, Spain.

出版信息

Rev Endocr Metab Disord. 2025 Apr 7. doi: 10.1007/s11154-025-09959-4.

Abstract

Childhood obesity is a global health problem, with its prevalence having tripled since 1975. The increase in its prevalence has been predominantly in developing countries, but also in those with high economic status. Nowadays, there are multiple obesity definitions, however, one of the most accurate is the one which defines obesity as the accumulation of excessive body adiposity and not as an body weight excess. Nevertheless, the body mass index (BMI) is the most frequently used tool for its classification, according to the cut-off points established by the Center for Disease Control and World Health Organization tables. In children and adolescents an adiposity excess is related to the appearance of cardiovascular disease in adulthood and with many comorbidities such as metabolic syndrome, insulin resistance, type 2 diabetes, hypertension and metabolic dysfunction-associated steatotic liver disease, among others. Currently, there is still controversy about which is the ideal indicator for measuring overweight and obesity. BMI is still used as a standardized measure but may miss cases in which body composition is pathological despite a BMI within the normal-weight category. An adequate knowledge of the impact on health of dysfunctional adiposity as well as its accurate diagnosis will allow health professionals to address this condition in a more precise and comprehensive manner, and substantially improve the associated cardiometabolic risk and prognosis.

摘要

儿童肥胖是一个全球性的健康问题,自1975年以来其患病率已增长了两倍。患病率的上升主要发生在发展中国家,但经济地位高的国家也存在这种情况。如今,肥胖有多种定义,然而,最准确的定义之一是将肥胖定义为身体脂肪过度堆积,而非体重超标。尽管如此,根据美国疾病控制中心和世界卫生组织表格所设定的临界点,体重指数(BMI)仍是最常用于肥胖分类的工具。在儿童和青少年中,脂肪过多与成年期心血管疾病的出现以及许多合并症有关,如代谢综合征、胰岛素抵抗、2型糖尿病、高血压和代谢功能障碍相关脂肪性肝病等。目前,关于衡量超重和肥胖的理想指标仍存在争议。BMI仍然被用作标准化测量方法,但可能会遗漏一些病例,即尽管BMI处于正常体重范围内,但身体成分却存在病理状况。充分了解功能失调性肥胖对健康的影响及其准确诊断,将使卫生专业人员能够更精确、全面地应对这种情况,并显著改善相关的心脏代谢风险和预后。

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