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改良斜外侧椎间融合术与单纯后路手术治疗退变性腰椎侧弯的比较

Comparison of Modified Oblique Lateral Interbody Fusion and Posterior-Only Approach in the Treatment of Degenerative Lumbar Scoliosis.

作者信息

Zhang Xiang, Wang Yongqiang, Lu Yilin, Li Junyu, Sun Zhuoran, Zeng Yan, Li Weishi, Yu Miao

机构信息

Department of Orthopedics, Peking University Third Hospital, Beijing, China.

Beijing Key Laboratory of Spinal Disease Research, Peking University Third Hospital, Beijing, China.

出版信息

Orthop Surg. 2025 Jun;17(6):1680-1690. doi: 10.1111/os.70038. Epub 2025 Apr 7.

Abstract

OBJECTIVE

Degenerative lumbar scoliosis (DLS) often requires surgical intervention, but traditional posterior-only approaches, despite their effectiveness, result in significant muscle damage and high complication rates. Minimally invasive techniques like oblique lumbar interbody fusion (OLIF) and the Wiltse approach are preferred for preserving posterior structures. However, the lack of controlled studies comparing combined approaches to traditional methods limits their efficacy evaluation. The purpose of this study is to explore the clinical and radiological outcomes of OLIF with posterior fixation through Wiltse approach versus a posterior-only approach in treating DLS.

METHODS

This retrospective study included 88 DLS patients underwent surgery from January 2019 to September 2021. The patients were divided into the OLIF group (n = 32) and the posterior group (n = 56). Comprehensive evaluations of clinical and radiological outcomes, including Cobb angle, coronal balance distance (CBD), sagittal vertical axis (SVA), thoracic kyphosis (TK), lumbar lordosis (LL), pelvic incidence (PI), pelvic tilt (PT), and sacral slope (SS) were conducted, with a subsequent subgrouping of OLIF group based on preoperative sagittal vertical axis (SVA) into Subgroup A (SVA ≤ 50 mm) and Subgroup B (SVA > 50 mm) for further analysis. The t-test or Wilcoxon's rank sum test is used to compare continuous variables, and the chi-square test is used to compare categorical variables.

RESULTS

The OLIF group had fewer fixation levels (4.25 ± 1.08 vs. 5.56 ± 2.04, p < 0.001) and shorter hospitalization (5.22 ± 2.25 d vs. 6.66 ± 2.16 d, p < 0.001), fewer drainage volume (371.94 mL vs. 1065.25 mL, p < 0.001), but longer surgical time. Postoperatively, the OLIF group showed better clinical outcomes. In both groups, Cobb angle, coronal balance distance, and sagittal spinal pelvic parameters improved significantly. The OLIF group achieved a lower SVA (23.84 mm ± 36.70 mm vs. 42.84 mm ± 36.25 mm, p = 0.027), which was not maintained at the final follow-up. Subgroup A maintained sagittal balance (34.55 mm ± 24.99 mm vs. 83.73 mm ± 61.90 mm, p = 0.029). Moreover, the OLIF group had fewer complications.

CONCLUSION

Minimally invasive multi-level OLIF with posterior fixation through Wiltse approach, as compared to the conventional posterior approach, has fewer fixation segments, offers comparable radiographic outcomes and, more importantly, superior clinical results. In addition, patients with a preoperative SVA > 50 mm could benefit from more fixation levels to maintain sagittal balance.

摘要

目的

退行性腰椎侧凸(DLS)通常需要手术干预,但传统的单纯后路手术方法尽管有效,却会导致严重的肌肉损伤和高并发症发生率。像斜外侧腰椎椎间融合术(OLIF)和Wiltse入路这样的微创技术因能保留后路结构而更受青睐。然而,缺乏将联合手术方法与传统方法进行对比的对照研究限制了对其疗效的评估。本研究的目的是探讨通过Wiltse入路行OLIF联合后路固定与单纯后路手术治疗DLS的临床和影像学结果。

方法

这项回顾性研究纳入了2019年1月至2021年9月期间接受手术的88例DLS患者。患者被分为OLIF组(n = 32)和后路组(n = 56)。对临床和影像学结果进行了全面评估,包括Cobb角、冠状面平衡距离(CBD)、矢状垂直轴(SVA)、胸椎后凸(TK)、腰椎前凸(LL)、骨盆入射角(PI)、骨盆倾斜角(PT)和骶骨倾斜角(SS),随后根据术前矢状垂直轴(SVA)将OLIF组进一步分为A亚组(SVA≤50 mm)和B亚组(SVA>50 mm)进行进一步分析。采用t检验或Wilcoxon秩和检验比较连续变量,采用卡方检验比较分类变量。

结果

OLIF组的固定节段更少(4.25±1.08 vs. 5.56±2.04,p<0.001),住院时间更短(5.22±2.25天 vs. 6.66±2.16天,p<0.001),引流量更少(371.94 mL vs. 1065.25 mL,p<0.001),但手术时间更长。术后,OLIF组显示出更好的临床结果。两组的Cobb角、冠状面平衡距离和矢状面脊柱骨盆参数均有显著改善。OLIF组的SVA更低(23.84 mm±36.70 mm vs. 42.84 mm±36.25 mm,p = 0.027),但在最终随访时未维持。A亚组维持了矢状面平衡(34.55 mm±24.99 mm vs. 83.73 mm±61.90 mm,p = 0.029)。此外,OLIF组的并发症更少。

结论

与传统后路手术相比,通过Wiltse入路行微创多节段OLIF联合后路固定具有更少的固定节段,提供了相当的影像学结果,更重要的是,临床效果更佳。此外,术前SVA>50 mm的患者可能受益于更多的固定节段以维持矢状面平衡。

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