Spinnato Paolo, Colangeli Marco, Rinaldi Raffaella, Ponti Federico
Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Orthopaedic Oncology Unit, IRCCS Istituto Ortopedico Rizzoli, 40136 Bologna, Italy.
Diagnostics (Basel). 2023 Jul 12;13(14):2350. doi: 10.3390/diagnostics13142350.
CT-guided bone biopsies are currently the diagnostic tool of choice for histopathological (and microbiological) diagnoses of skeletal lesions. Several research works have well-demonstrated their safety and feasibility in almost all skeletal regions. This comprehensive review article aims at summarizing the general concepts in regard to bone biopsy procedures, current clinical indications, the feasibility and the diagnostic yield in different skeletal sites, particularly in the most delicate and difficult-to-reach ones. The choice of the correct imaging guidance and factors affecting the diagnostic rate, as well as possible complications, will also be discussed. Since the diagnostic yield, technical difficulties, and complications risk of a CT-guided bone biopsy significantly vary depending on the different skeletal sites, subdivided analyses of different anatomical sites are provided. The information included in the current review article may be useful for clinicians assisting patients with possible bone neoplasms, as well as radiologists involved in the imaging diagnoses of skeletal lesions and/or in performing bone biopsies.
CT引导下的骨活检目前是骨骼病变组织病理学（及微生物学）诊断的首选诊断工具。多项研究已充分证明其在几乎所有骨骼区域的安全性和可行性。这篇综述文章旨在总结骨活检程序的一般概念、当前临床适应症、不同骨骼部位的可行性和诊断率，特别是在最精细和最难到达的部位。还将讨论正确成像引导的选择、影响诊断率的因素以及可能的并发症。由于CT引导下骨活检的诊断率、技术难度和并发症风险因不同骨骼部位而异，因此本文提供了不同解剖部位的细分分析。本文所包含的信息可能对协助可能患有骨肿瘤患者的临床医生以及参与骨骼病变影像诊断和/或进行骨活检的放射科医生有用。
