Melichar V, Razová M, Janovsky M
Padiatr Padol. 1977;12(1):48-54.
Nitrogen balance studies were performed in the course of parenteral nutrition in the first 5 days of life in three groups of low birth weight newborns (I. group = 12 premature, 27.--30. gestational week, b. w. M = 1298 g, II. group = a) 7 prematures, 27.--31.g.w.,b.w.M = 1295 g,b) 5 small for date prematures, 29.--32.g.w.,b.w.M = 1208 g, III. group = 10 prematures, 31.--36.g.w.,b.w. M = 1751 g). Losses of nitrogen via urine in extreme prematures during the adaptation period are higher than in full term or moderate prematures. Increased volume of parenteral nutrition (glucose, fat emulsion) and increased caloric quotient did not produce a significant restriction of N-losses via urine. No difference was found in N-losses between extreme prematures and small for date prematures of similar birth weight/group IIa): IIb)/. Aminoacids (cca 500 mg N/kg body weight/24 hrs) given on the second day of life were well retained; increased losses of N represented about 20% of N infused.
对三组低出生体重新生儿在出生后前5天的肠外营养过程中进行了氮平衡研究(第一组=12名早产儿,孕龄27 - 30周,平均体重1298克;第二组=a)7名早产儿,孕龄27 - 31周,平均体重1295克,b)5名小于胎龄早产儿,孕龄29 - 32周,平均体重1208克;第三组=10名早产儿,孕龄31 - 36周,平均体重1751克)。极早产儿在适应期经尿液的氮损失高于足月儿或中度早产儿。肠外营养(葡萄糖、脂肪乳剂)量的增加和热量系数的增加并未显著限制经尿液的氮损失。在出生体重相似的极早产儿和小于胎龄早产儿(第二组a):第二组b)之间,未发现氮损失有差异。出生后第二天给予的氨基酸(约500毫克氮/千克体重/24小时)保留良好;增加的氮损失约占输注氮的20%。