Karamarkou Christina, Babady Mehran, Maltsinioti Charalampia, Bruder Oliver
Elisabeth Krankenhaus Essen, Essen, Germany.
Echocardiography. 2025 Apr;42(4):e70146. doi: 10.1111/echo.70146.
Hypertrophic cardiomyopathy (HCM) is a genetic cardiac disorder associated with significant morbidity and mortality. This review highlights the essential role of multimodal imaging-transthoracic echocardiography (TTE), cardiac magnetic resonance (CMR), and cardiac computed tomography (CCT)-in the diagnosis, risk stratification, and management of HCM. TTE remains the first-line tool, while advanced techniques like CMR and CCT offer enhanced accuracy in tissue characterization, fibrosis detection, and procedural planning. By integrating these imaging modalities, clinicians can adopt a precision medicine approach, enabling tailored treatment strategies that address individual patient needs. This comprehensive use of imaging not only enhances clinical decision-making but also holds the potential to improve long-term outcomes for patients with HCM.
肥厚型心肌病(HCM)是一种与显著发病率和死亡率相关的遗传性心脏疾病。本综述强调了多模态成像——经胸超声心动图(TTE)、心脏磁共振成像(CMR)和心脏计算机断层扫描(CCT)——在HCM诊断、风险分层和管理中的重要作用。TTE仍然是一线工具,而CMR和CCT等先进技术在组织特征描述、纤维化检测和手术规划方面提供了更高的准确性。通过整合这些成像方式,临床医生可以采用精准医疗方法,制定满足个体患者需求的个性化治疗策略。这种对成像的全面应用不仅能加强临床决策,还具有改善HCM患者长期预后的潜力。