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测量胰岛素的力学性质:克服实时、即时护理胰岛素传感挑战的潜在解决方案。

Measuring the Mechanical Properties of Insulin: A Potential Solution to Overcoming the Challenges of Real-Time, Point-of-Care Insulin Sensing.

作者信息

Young Emily, Gutschmidt Stefanie, Chase J Geoffrey

机构信息

Department of Mechanical Engineering, University of Canterbury, Christchurch, New Zealand.

出版信息

J Diabetes Sci Technol. 2025 Apr 9:19322968251331072. doi: 10.1177/19322968251331072.

Abstract

It is well established real-time, point-of-care capabilities for insulin sensing would provide valuable insight to enhance diabetes management and care in the human body. However, such suitable technology has not yet been developed or commercialized. While not comprehensive, this commentary provides a concise summary of the motivation and challenges of developing real-time, point-of-care insulin sensing technology and offers some comments on current approaches. This short research analysis presents a new perspective on the problem and introduces a future potential solution via measuring the mechanical properties of insulin and discusses the challenges foreseen in the feasibility of this proposed solution.

摘要

实时、即时护理的胰岛素传感功能已得到充分证实,可为改善人体糖尿病管理与护理提供宝贵见解。然而,此类适用技术尚未得到开发或商业化。本评论虽不全面,但简要总结了开发实时、即时护理胰岛素传感技术的动机与挑战,并对当前方法提出了一些看法。这项简短的研究分析从新角度审视了该问题,通过测量胰岛素的机械性能介绍了一种未来可能的解决方案,并讨论了该方案可行性中可预见的挑战。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d2f5/11982062/291ff1f8b8db/10.1177_19322968251331072-fig1.jpg

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