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冠状动脉异常起源:诊断难题

Anomalous Origin of Coronary Arteries: A Diagnostic Dilemma.

作者信息

Madanat Luai, Jabri Ahmad, Gallagher Michael, Cami Elvis, Bloomingdale Richard

机构信息

Department of Cardiovascular Medicine, William Beaumont University Hospital Corewell Health East, MI.

Oakland University William Beaumont School of Medicine Rochester, MI.

出版信息

US Cardiol. 2025 Apr 1;19:e09. doi: 10.15420/usc.2024.57. eCollection 2025.

DOI:10.15420/usc.2024.57
PMID:40201305
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11976735/
Abstract

With the increasing use of imaging for screening and diagnostic purposes, particularly coronary CT angiography, the number of adult patients diagnosed with anomalous origin of the coronary arteries (AOCA) has risen significantly. While current guidelines offer a general framework for managing and treating AOCA, patients present with diverse anomalies, symptoms, and clinical presentations, making broad recommendations less universally applicable. Notably, a wide range of treatment options exists, but there is no clear consensus on the best intervention strategy. Presented here are three cases of AOCA emphasizing the anatomical variations, clinical presentations, and the utility of coronary CT angiography in delineating anatomy and identifying high-risk features.

摘要

随着成像技术越来越多地用于筛查和诊断目的,尤其是冠状动脉CT血管造影,被诊断为冠状动脉异常起源(AOCA)的成年患者数量显著增加。虽然当前指南为AOCA的管理和治疗提供了一个总体框架,但患者存在各种不同的异常、症状和临床表现,使得广泛的建议并非普遍适用。值得注意的是,存在多种治疗选择,但对于最佳干预策略尚无明确共识。本文介绍了三例AOCA病例,强调了解剖变异、临床表现以及冠状动脉CT血管造影在描绘解剖结构和识别高危特征方面的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1637/11976735/679398f2e0b1/usc-19-e09-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1637/11976735/7a394de4bdff/usc-19-e09-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1637/11976735/37e29bd19c58/usc-19-e09-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1637/11976735/679398f2e0b1/usc-19-e09-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1637/11976735/7a394de4bdff/usc-19-e09-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1637/11976735/37e29bd19c58/usc-19-e09-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1637/11976735/679398f2e0b1/usc-19-e09-g003.jpg

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本文引用的文献

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Management of Adults With Anomalous Aortic Origin of the Coronary Arteries: State-of-the-Art Review.成人冠状动脉异常起源的管理:最新综述
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Coronary CT FFR vs Invasive Adenosine and Dobutamine FFR in a Right Anomalous Coronary Artery.右冠状动脉异常时冠状动脉CT血流储备分数与有创腺苷和多巴酚丁胺血流储备分数的比较
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Physiological Evaluation of Anomalous Aortic Origin of a Coronary Artery Using Computed Tomography-Derived Fractional Flow Reserve.采用 CT 衍生的血流储备分数对冠状动脉异常起源的生理学评估。
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2020 ESC Guidelines for the management of adult congenital heart disease.2020年欧洲心脏病学会成人先天性心脏病管理指南。
Eur Heart J. 2021 Feb 11;42(6):563-645. doi: 10.1093/eurheartj/ehaa554.
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Discrepancy Between SPECT and Dobutamine FFR in Right Anomalous Coronary Artery Undergoing Unroofing.右冠状动脉异常经去顶术时单光子发射计算机断层扫描(SPECT)与多巴酚丁胺血流储备分数(FFR)之间的差异
Ann Thorac Surg. 2020 Dec;110(6):e569. doi: 10.1016/j.athoracsur.2020.05.128. Epub 2020 Jul 21.
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