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使用倾向评分匹配法的机器人与腹腔镜胃切除术的临床结局:韩国一家高容量胃癌中心的5年数据。

Clinical outcomes of robotic and laparoscopic gastrectomy using propensity score matching method: Data of 5-year period in a Korean high-volume gastric cancer center.

作者信息

Cho Yo-Seok, Berlth Felix, Kim Jeesun, Suh Yun-Suhk, Kong Seong-Ho, Park Do Joong, Lee Hyuk-Joon, Yang Han-Kwang

机构信息

Department of Surgery, Seoul National University Hospital, Seoul, Republic of Korea.

Department of General, Visceral-and Transplant Surgery, University Hospital Tübingen, Tübingen, Germany.

出版信息

Eur J Surg Oncol. 2025 Aug;51(8):110014. doi: 10.1016/j.ejso.2025.110014. Epub 2025 Apr 4.

Abstract

INTRODUCTION

Despite the theoretical advantages of Robotic gastrectomy (RG) over laparoscopic gastrectomy (LG), the benefit of RG compared to LG remains controversial. To address this controversy, we evaluated the outcomes of RG compared to LG in the high-volume gastric cancer center.

MATERIALS AND METHODS

This single-center retrospective cohort study enrolled patients of RG and LG from January 2013 to December 2017 using propensity score matching. Results of operation, and overall survival were analyzed.

RESULTS

For RG, 268 patients were enrolled, and 733 patients with LG were matched. The four gastric methods were matched at the following ratios; Distal gastrectomy (RG: 35.8 % vs LG: 38.7 %), Total gastrectomy (RG: 16.0 % vs LG: 13.9 %), Pylorus-preserving gastrectomy (RG: 46.3 % vs LG: 44.7 %), Proximal gastrectomy (RG: 1.9 % vs LG: 2.6 %) The median number of retrieved lymph nodes (RG: 36.0 vs LG: 37.0, p = 0.247) and supra-pancreatic lymph nodes (RG: 8.0 vs LG: 7.0, p = 0.647), showed no difference. No difference was observed in complications (RG: 21.3 % vs LG: 21.4 %, p = 1.000), and severe complications (RG: 13.1 % vs LG: 12.7 %, p = 0.961) The 5-year overall survival was not significantly different (RG: 94.8 % vs LG: 93.1 %, hazard ratio: 0.76, 95 % confidence interval: 0.41-1.40, p = 0.379).

CONCLUSION

Our study observed no advantage in RG compared to LG regarding short-term and oncologic outcomes. To take advantage of RG, developing new articulating efficient devices would be necessary.

摘要

引言

尽管机器人胃癌切除术(RG)相较于腹腔镜胃癌切除术(LG)在理论上具有优势,但RG与LG相比的益处仍存在争议。为解决这一争议,我们在高容量胃癌中心评估了RG与LG的手术结果。

材料与方法

这项单中心回顾性队列研究使用倾向评分匹配法纳入了2013年1月至2017年12月期间接受RG和LG手术的患者。分析了手术结果和总生存期。

结果

对于RG组,纳入了268例患者,匹配了733例LG组患者。四种胃癌手术方式的匹配比例如下:远端胃切除术(RG组:35.8% vs LG组:38.7%),全胃切除术(RG组:16.0% vs LG组:13.9%),保留幽门胃切除术(RG组:46.3% vs LG组:44.7%),近端胃切除术(RG组:1.9% vs LG组:2.6%)。回收淋巴结的中位数(RG组:36.0个 vs LG组:37.0个,p = 0.247)和胰上淋巴结(RG组:8.0个 vs LG组:7.0个,p = 0.647)无差异。并发症(RG组:21.3% vs LG组:21.4%,p = 1.000)和严重并发症(RG组:13.1% vs LG组:12.7%,p = 0.961)方面未观察到差异。5年总生存期无显著差异(RG组:94.8% vs LG组:93.1%,风险比:0.76,95%置信区间:0.41-1.40,p = 0.379)。

结论

我们的研究观察到,在短期和肿瘤学结果方面,RG与LG相比没有优势。要利用RG的优势,开发新的关节式高效设备将是必要的。

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