Mei Xiaoxiao, Yeung Wing-Fai, Hu Yule, He Mengting, Lu Wenze, Bayuo Jonathan, Lantta Tella, Li Yan
School of Nursing, The Hong Kong Polytechnic University, Hong Kong.
Department of Nursing Science, University of Turku, Turku, Finland.
Arch Psychiatr Nurs. 2025 Apr;55:151855. doi: 10.1016/j.apnu.2025.151855. Epub 2025 Mar 10.
Research on mental health problems in individuals with ankylosing spondylitis (AS) has rapidly expanded since 2013. However, the evidence in this field can appear fragmented due to the limited number of existing reviews that synthesize research findings.
To map the evidence regarding the prevalence, correlated factors, and interventions for mental health problems in the AS population.
This review followed Arksey and O'Malley's framework and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Extension for Scoping Reviews. Six electronic databases were searched for studies published in English since January 2013. Study quality was assessed using the Mixed Methods Appraisal Tool, and data were narratively summarized and reported.
Seventy articles were included in this review. The prevalence rates of depression, anxiety, and sleep disorders ranged from 3.1 % to 66.0 %, 2.7 % to 78.0 %, and 1.7 % to 71.7 %, respectively. Correlated factors included sociodemographic variables, disease-related aspects, physical symptoms and function, and psycho-behavioral factors. Interventions were categorized into physical exercise, therapeutic, and psychosocial approaches.
Mental health problems are prevalent among individuals with AS, and the correlated factors are multidimensional. Interventions aimed at physical function, disease activity, and cognitive functions have been identified as critical strategies for addressing mental health problems. Further research is needed to design and develop effective interventions targeting these correlated factors, particularly psycho-social interventions, to prevent future deterioration.
自2013年以来，关于强直性脊柱炎（AS）患者心理健康问题的研究迅速增加。然而，由于综合研究结果的现有综述数量有限，该领域的证据可能显得零散。
梳理有关AS患者心理健康问题的患病率、相关因素及干预措施的证据。
本综述遵循阿克西和奥马利的框架以及系统评价和Meta分析扩展版的范围综述的首选报告项目。检索了6个电子数据库，以查找自2013年1月以来发表的英文研究。使用混合方法评估工具评估研究质量，并对数据进行叙述性总结和报告。
本综述纳入了70篇文章。抑郁症、焦虑症和睡眠障碍的患病率分别为3.1%至66.0%、2.7%至78.0%和1.7%至71.7%。相关因素包括社会人口统计学变量、疾病相关方面、身体症状和功能以及心理行为因素。干预措施分为体育锻炼、治疗和心理社会方法。
心理健康问题在AS患者中普遍存在，且相关因素具有多维度性。针对身体功能、疾病活动和认知功能的干预措施已被确定为解决心理健康问题的关键策略。需要进一步研究来设计和开发针对这些相关因素的有效干预措施，尤其是心理社会干预措施，以防止病情进一步恶化。
