Agarwal Lokesh, Rathore Kaushal Singh, Varshney Vaibhav Kumar, Soni Subhash, Selvakumar B, Varshney Peeyush, Agarwal Ayushi, Verma Vikrant, Sureka Binit, Yadav Taruna
Department of Surgical Gastroenterology, All India Institute of Medical Sciences, Jodhpur, Rajasthan, 342005, India.
Department of Diagnostic and Interventional Radiology, All India Institute of Medical Sciences, Jodhpur, India.
Dig Dis Sci. 2025 Apr 9. doi: 10.1007/s10620-025-09025-8.
Groove pancreatitis (GP) is a rare form of focal chronic pancreatitis characterized by inflammation in the anatomic space between the duodenal wall and the head of the pancreas. This study aims to review the surgical experience in diagnosing and managing GP at a tertiary healthcare center in India.
A single-center, retrospective, cross-sectional study was conducted at the All India Institute of Medical Sciences, Jodhpur, between January 2017 and December 2023. The study included all patients with clinical, radiologic, and pathologic confirmation of GP. Data on demographics, clinical history, radiologic imaging, surgical intervention, and perioperative outcomes were collected. Pain and quality of life (QOL) were assessed preoperatively and postoperatively at 3, 6, and 12 months using the Izbicki pain score and the SF-36 questionnaire.
During the study period, eleven patients with a clinico-radiologic diagnosis of GP underwent surgery. The median diagnostic delay was 14 months. Common presenting symptoms included abdominal pain (100%), gastric outlet obstruction (81.8%), and obstructive jaundice (18.2%). The majority of patients had a history of tobacco and alcohol abuse. Pancreato-duodenectomy (PD) was performed in ten cases, while one patient underwent a bypass procedure. Post-operative complications included post-operative pancreatic fistula (27.3%), delayed gastric emptying (54.5%), and post-pancreatectomy hemorrhage (9.1%). Three patients developed Clavien-Dindo IIIa complications. The median follow-up duration was 19 (IQR: 12-22) months. At the 12-month follow-up, pain and QOL scores showed significant improvement across all domains when compared to pre-operative measurements (p < 0.001). Three patients had recurrent pancreatitis due to resumption of alcohol and tobacco use.
GP is a rare and complex condition with significant challenges in diagnosis and management. Surgical treatment, particularly PD, provides effective symptom relief and improves QOL in most patients.
沟部胰腺炎（GP）是一种罕见的局灶性慢性胰腺炎，其特征是十二指肠壁与胰头之间的解剖间隙发生炎症。本研究旨在回顾印度一家三级医疗中心诊断和治疗GP的手术经验。
2017年1月至2023年12月期间，在焦特布尔全印度医学科学研究所进行了一项单中心、回顾性横断面研究。该研究纳入了所有经临床、影像学和病理学确诊为GP的患者。收集了人口统计学、临床病史、影像学检查、手术干预和围手术期结果的数据。术前以及术后3、6和12个月使用伊兹比基疼痛评分和SF-36问卷评估疼痛和生活质量（QOL）。
在研究期间，11例临床影像学诊断为GP的患者接受了手术。中位诊断延迟为14个月。常见的表现症状包括腹痛（100%）、胃出口梗阻（81.8%）和梗阻性黄疸（18.2%）。大多数患者有吸烟和酗酒史。10例患者接受了胰十二指肠切除术（PD），1例患者接受了旁路手术。术后并发症包括术后胰瘘（27.3%）；胃排空延迟（54.5%）和胰腺切除术后出血（9.1%）。3例患者出现Clavien-Dindo IIIa级并发症。中位随访时间为19（四分位间距：12 - 22）个月。在12个月的随访中，与术前测量相比，所有领域的疼痛和QOL评分均有显著改善（p < 0.001）。3例患者因恢复吸烟和饮酒而复发胰腺炎。
GP是一种罕见且复杂的疾病，在诊断和治疗方面存在重大挑战。手术治疗，尤其是PD，可有效缓解症状并改善大多数患者的QOL。
