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Overlap Between Gastroesophageal Reflux Disease and Functional Dyspepsia: Do We Need a New Management Paradigm?

作者信息

Byun So Young, Jung Kee Wook

机构信息

Department of Gastroenterology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

J Neurogastroenterol Motil. 2025 Apr 30;31(2):129-130. doi: 10.5056/jnm25030.

DOI:10.5056/jnm25030
PMID:40205891
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11986656/
Abstract
摘要

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Overlap Between Gastroesophageal Reflux Disease and Functional Dyspepsia: Do We Need a New Management Paradigm?胃食管反流病与功能性消化不良的重叠：我们是否需要一种新的管理模式？
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本文引用的文献

1
Overlapping Reflux Symptoms in Functional Dyspepsia Are Mostly Unrelated to Gastroesophageal Reflux.功能性消化不良中的重叠反流症状大多与胃食管反流无关。
J Neurogastroenterol Motil. 2025 Apr 30;31(2):218-226. doi: 10.5056/jnm24091.
2
Breaking Barriers in Functional Dyspepsia: A Systematic Review and Meta-analysis on Duodenal Tight Junction Protein Expression.功能性消化不良的突破障碍：十二指肠紧密连接蛋白表达的系统评价和荟萃分析
J Neurogastroenterol Motil. 2024 Jul 30;30(3):281-289. doi: 10.5056/jnm24013.
3
Efficacy of Tegoprazan in Patients With Functional Dyspepsia: A Prospective, Multicenter, Single-arm Study.替戈拉赞治疗功能性消化不良患者的疗效：一项前瞻性、多中心、单臂研究。
J Neurogastroenterol Motil. 2024 Jul 30;30(3):313-321. doi: 10.5056/jnm23150. Epub 2024 May 4.
4
Clinical Trial: Efficacy of Mosapride Controlled-release and Nortriptyline in Patients With Functional Dyspepsia: A Multicenter, Double-placebo, Double-blinded, Randomized Controlled, Parallel Clinical Study.临床试验：莫沙必利缓释片与去甲替林治疗功能性消化不良的疗效：一项多中心、双安慰剂、双盲、随机对照、平行的临床研究。
J Neurogastroenterol Motil. 2024 Jan 30;30(1):106-115. doi: 10.5056/jnm23147.
5
The Effect of STW5 (Iberogast) on Reflux Symptoms in Patients With Concurrent Dyspeptic Symptoms: A Double-blind Randomized Placebo-controlled Crossover Trial.STW5（伊贝戈斯特）对伴有消化不良症状的患者反流症状的影响：一项双盲随机安慰剂对照交叉试验。
J Neurogastroenterol Motil. 2024 Jan 30;30(1):54-63. doi: 10.5056/jnm23014. Epub 2023 Dec 2.
6
Characteristics and Risk Factors of Functional Dyspepsia Fulfilling the Rome IV Criteria Overlapping With Gastroesophageal Reflux Disease, Irritable Bowel Syndrome, and Functional Constipation in South China.符合罗马IV标准的功能性消化不良在中国南方与胃食管反流病、肠易激综合征和功能性便秘重叠的特征及危险因素
J Neurogastroenterol Motil. 2024 Apr 30;30(2):184-193. doi: 10.5056/jnm23084. Epub 2023 Sep 27.
7
Updates to the modern diagnosis of GERD: Lyon consensus 2.0.胃食管反流病现代诊断的更新：里昂共识 2.0。
Gut. 2024 Jan 5;73(2):361-371. doi: 10.1136/gutjnl-2023-330616.
8
Overlap of disorders of gut-brain interaction: a systematic review and meta-analysis.肠脑互动障碍的重叠：系统评价和荟萃分析。
Lancet Gastroenterol Hepatol. 2023 Jul;8(7):646-659. doi: 10.1016/S2468-1253(23)00102-4. Epub 2023 May 18.
9
Asia-Pacific guidelines for managing functional dyspepsia overlapping with other gastrointestinal symptoms.亚太地区功能性消化不良合并其他胃肠道症状的管理指南
J Gastroenterol Hepatol. 2023 Feb;38(2):197-209. doi: 10.1111/jgh.16046. Epub 2022 Nov 28.
10
Alterations to the duodenal microbiota are linked to gastric emptying and symptoms in functional dyspepsia.十二指肠微生物群的改变与功能性消化不良的胃排空及症状有关。
Gut. 2023 May;72(5):929-938. doi: 10.1136/gutjnl-2021-326158. Epub 2022 Sep 27.