Inayat Hamza, Branch Anna, Armstrong James J, Juncal Verena, Casserly Courtney
Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.
Department of Clinical Neurological Sciences, Schulich School of Medicine & Dentistry, Western University, London, Ontario, Canada.
IDCases. 2024 Oct 15;38:e02095. doi: 10.1016/j.idcr.2024.e02095. eCollection 2024.
This case report aims to emphasize the significance of the ocular manifestations in individuals with West Nile Virus (WNV) infection, with primary neurological involvement. By presenting a case of chorioretinal scarring secondary to WNV, we highlight the importance of a thorough ophthalmological evaluation in suspected cases of WNV to identify potential sight-threatening complications.
A 63-year-old woman presented with neurological symptoms following a trip to Denver, USA, including headaches, fever, and decreased consciousness. Despite initial treatment for suspected meningoencephalitis, her condition deteriorated, leading to focal seizures and profound weakness. Ophthalmological examination revealed chorioretinal lesions consistent with WNV retinopathy.
and Importance: WNV can present with neurological symptoms, and ocular complications can lead to significant visual impairment. This case report highlights the importance of asking individuals with suspected WNV about ocular symptoms. Despite the absence of a preventive treatment for ocular manifestations, clinicians must stay attentive to ocular symptoms in patients to mitigate potential complications, such as chorioretinal neovascularization, which can be treated with anti-vascular endothelial growth factor therapy injections.
本病例报告旨在强调西尼罗河病毒（WNV）感染且主要累及神经系统的个体中眼部表现的重要性。通过呈现一例WNV继发脉络膜视网膜瘢痕形成的病例，我们强调在疑似WNV病例中进行全面眼科评估以识别潜在威胁视力并发症的重要性。
一名63岁女性在美国丹佛旅行后出现神经系统症状，包括头痛、发热和意识减退。尽管最初对疑似脑膜脑炎进行了治疗，但她的病情恶化，导致局灶性癫痫发作和严重虚弱。眼科检查发现与WNV视网膜病变一致的脉络膜视网膜病变。
WNV可表现为神经系统症状，眼部并发症可导致严重视力损害。本病例报告强调了询问疑似WNV感染者眼部症状的重要性。尽管目前尚无针对眼部表现的预防性治疗方法，但临床医生必须关注患者的眼部症状，以减轻潜在并发症，如脉络膜视网膜新生血管形成，可通过抗血管内皮生长因子治疗性注射进行治疗。
