Wilson J
Am J Med Technol. 1977 Feb;43(2):147-55.
Polyagglutination is a condition in which the erythrocyte membrane has been altered so that the red cell becomes agglutinable with the majority of adult serums. In many instances, it can be shown that the red cell membrane alteration has resulted in activation of one (or more) latent antigens, i.e. T, Tk, or Tn. Adult serums normally contain IgM antibodies directed against these hidden antigens. When these latent receptors are exposed, the cells will be found to be polyagglutinable upon subsequent testing with these serums. This review describes the serologic procedures applicable for identification and resolution of the problems each type of polyagglutinable cell creates for the blood bank.
多凝集现象是一种红细胞膜发生改变，致使红细胞能与大多数成人血清发生凝集的状况。在许多情况下，可以证明红细胞膜的改变导致了一种（或多种）潜在抗原的激活，即T、Tk或Tn。成人血清通常含有针对这些隐蔽抗原的IgM抗体。当这些潜在受体暴露时，随后用这些血清进行检测时会发现细胞具有多凝集性。本综述描述了适用于识别和解决每种类型的多凝集细胞给血库带来问题的血清学方法。
