Suppr超能文献

人类可遗传基因组编辑及其治理:科学家和治理专业人士的观点

Human Heritable Genome Editing and its Governance: Views of Scientists and Governance Professionals.

作者信息

Cadigan R Jean, Waltz Margaret, Conley John M, Major Rami M, Branch Elizabeth K, Juengst Eric T, Flatt Michael A

机构信息

Department of Social Medicine, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.

School of Law, University of North Carolina-Chapel Hill, Chapel Hill, NC, USA.

出版信息

New Genet Soc. 2024;43(1). doi: 10.1080/14636778.2024.2404061. Epub 2024 Sep 20.

Abstract

Heritable human genome editing has garnered significant attention in scholarly and lay media, yet questions remain about whether, when, and how heritable genome editing ought to proceed. Drawing on interviews with scientists who use genome editing in their research and professionals engaged in human genome editing governance efforts, we examine their views on the permissibility of heritable genome editing and the governance strategies they see as necessary and realistic. For both issues, we found divergent views from respondents. We place the views of these scientists and governance professionals within the context of the larger bioethical discussion of heritable genome editing governance, along a continuum of hard to soft approaches. These respondents' views highlight the challenges of various hard forms of governance and the potential virtues of soft governance approaches.

摘要

可遗传的人类基因组编辑在学术和大众媒体中都引起了广泛关注,但关于可遗传基因组编辑是否应该进行、何时进行以及如何进行,仍然存在诸多问题。通过对在研究中使用基因组编辑的科学家以及参与人类基因组编辑治理工作的专业人员进行访谈,我们考察了他们对可遗传基因组编辑可允许性的看法以及他们认为必要且现实的治理策略。对于这两个问题,我们发现受访者的观点存在分歧。我们将这些科学家和治理专业人员的观点置于关于可遗传基因组编辑治理的更大生物伦理讨论背景下,沿着从强硬到温和的方法连续统进行分析。这些受访者的观点凸显了各种强硬治理形式的挑战以及温和治理方法的潜在优点。

相似文献

5
Governance of Heritable Human Gene Editing World-Wide and Beyond.人类可遗传基因编辑的全球治理及其他问题
Int J Environ Res Public Health. 2022 May 31;19(11):6739. doi: 10.3390/ijerph19116739.
9
10
Global Governance of Human Genome Editing: What Are the Rules?人类基因组编辑的全球治理:规则是什么?
Annu Rev Genomics Hum Genet. 2021 Aug 31;22:385-405. doi: 10.1146/annurev-genom-111320-091930. Epub 2021 Mar 5.

引用本文的文献

本文引用的文献

1
Stakeholder Involvement in the Governance of Human Genome Editing in Japan.日本利益相关者对人类基因组编辑治理的参与。
Asian Bioeth Rev. 2023 Apr 26;15(4):431-455. doi: 10.1007/s41649-023-00251-8. eCollection 2023 Oct.
4
Seven open questions in the futures of human genome editing.人类基因组编辑未来的七个开放性问题。
Futures. 2023 May;149. doi: 10.1016/j.futures.2023.103138. Epub 2023 Mar 21.
5
Human genome editing: ensuring responsible research.人类基因组编辑:确保负责任的研究。
Lancet. 2023 Mar 18;401(10380):877. doi: 10.1016/S0140-6736(23)00560-3.
6
Governing nonconventional genetic experimentation.管理非常规基因实验。
J Law Biosci. 2023 Mar 9;10(1):lsad003. doi: 10.1093/jlb/lsad003. eCollection 2023 Jan-Jun.
7
China sets new ethics rules for human studies.中国为人体研究制定了新的伦理规则。
Science. 2023 Mar 10;379(6636):970. doi: 10.1126/science.adh4963. Epub 2023 Mar 9.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验