Gao Jianhong, Wei Zhenhua, Wang Zhengyu, Zhang Yun
Hubei Minzu University, Central Hospital of Enshi Tujia and Miao Autonomous Prefecture, Enshi Hubei, 445000, China; Health Medical Center, Hubei Minzu University, Enshi, Hubei, 445000, China.
Health Medical Center, Hubei Minzu University, Enshi, Hubei, 445000, China.
J Stroke Cerebrovasc Dis. 2025 Jun;34(6):108308. doi: 10.1016/j.jstrokecerebrovasdis.2025.108308. Epub 2025 Apr 8.
This study aims to analyze the disease burden attributed to ischemic stroke related to low-fiber diets (IFD-IS) from 1990 to 2021, utilizing data from the Global Burden of Disease (GBD) database to identify trends and influencing factors of the disease burden.
We conducted a comprehensive analysis of the number of deaths, Disability-Adjusted Life Years (DALYs), Years of Life Lost (YLLs), and Years Lost due to Disability (YLDs) associated with IFD-IS, covering various regions and populations. Statistical methods, including breakpoint regression, decomposition analysis, health inequality analysis, and forecasting analysis, were employed to assess trends and their correlation with the Sociodemographic Index (SDI).
The findings indicate that deaths, DALYs, YLLs, and YLDs related to IFD-IS have gradually increased globally, with a significantly higher burden in males compared to females. Notable regional disparities were observed, particularly with heavier burdens in China and sub-Saharan Africa. Higher SDI regions demonstrated better control over disease burdens, while aging and population growth were the primary factors contributing to the increase. Additionally, the trend of health inequality related to IFD-IS has slightly diminished, although it is projected that the disease burden will continue to rise by 2040.
This study underscores the necessity of implementing targeted public health interventions for IFD-IS, particularly in low SDI regions. Enhancing dietary education and resource allocation can significantly mitigate the rising trend of IFD-IS. Ongoing monitoring and research are crucial for formulating effective health policies to address this public health challenge.
本研究旨在利用全球疾病负担(GBD)数据库的数据,分析1990年至2021年低纤维饮食相关缺血性卒中(IFD-IS)的疾病负担,以确定疾病负担的趋势和影响因素。
我们对与IFD-IS相关的死亡人数、伤残调整生命年(DALYs)、生命损失年数(YLLs)和残疾损失年数(YLDs)进行了全面分析,涵盖了不同地区和人群。采用了包括断点回归、分解分析、健康不平等分析和预测分析在内的统计方法,以评估趋势及其与社会人口指数(SDI)的相关性。
研究结果表明,全球范围内与IFD-IS相关的死亡、DALYs、YLLs和YLDs呈逐渐上升趋势,男性的负担明显高于女性。观察到显著的地区差异,特别是中国和撒哈拉以南非洲的负担较重。SDI较高的地区对疾病负担的控制较好,而老龄化和人口增长是导致负担增加的主要因素。此外,与IFD-IS相关的健康不平等趋势略有减弱,尽管预计到2040年疾病负担将继续上升。
本研究强调了针对IFD-IS实施有针对性的公共卫生干预措施的必要性,特别是在低SDI地区。加强饮食教育和资源分配可以显著缓解IFD-IS的上升趋势。持续的监测和研究对于制定有效的卫生政策以应对这一公共卫生挑战至关重要。