Dreizen S, McCredie K B, Dicke K A, Zander A R, Peters L J
Postgrad Med. 1979 Nov;66(5):187-93, 196. doi: 10.1080/00325481.1979.11715304.
In recent years bone marrow transplantation has become increasingly feasible for treating adult acute leukemia unresponsive to chemotherapy. However, the technique is not without significant intrinsic morbidity. The mouth is a singularly sensitive reflector of the cytotoxic, infectious, and hemorrhagic complications and of the graft-vs-host reactions associated with bone marrow transplantation in refractory acute leukemia.
近年来,骨髓移植已越来越多地用于治疗对化疗无反应的成人急性白血病。然而,这项技术并非没有显著的内在发病率。口腔是细胞毒性、感染性和出血性并发症以及与难治性急性白血病骨髓移植相关的移植物抗宿主反应的一个特别敏感的反映部位。