den Bleijker Natascha M, van Schothorst Myrthe M E, Blanken Tessa F, Hendriksen Ingrid J M, Cahn Wiepke, Deenik Jeroen
Scientific Research Department, GGz Centraal, Amersfoort, the Netherlands.
Department of Psychiatry, UMC Utrecht Brain Center, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Eur Psychiatry. 2025 Apr 11;68(1):e53. doi: 10.1192/j.eurpsy.2025.2442.
Unhealthy lifestyle behaviors are prevalent among people with mental illness (MI), affecting their physical and mental health. Most research has focused on the isolated effects of lifestyle behaviors, leaving the interconnectedness between these behaviors and health outcomes unexplored. This study aimed to examine these relationships and identify the most strongly connected lifestyle behavior or health outcome within a network.
We conducted a cross-sectional study with 423 inpatients with MI, receiving care as usual. Lifestyle behaviors, physical and mental health outcomes were assessed through questionnaires and routine data. A Gaussian Graphical Model was estimated, and strength centrality was calculated to identify the most influential nodes.
Mean age was 55.5 years, 42% were female, and 41% were diagnosed with schizophrenia. Psychological and physical quality of life (QoL), nighttime sleep problems, and overall sleep quality were the most strongly connected nodes. Sleep was strongly associated with physical QoL. Furthermore, there were negative associations between healthy food intake and cholesterol ratio, and positive associations between daily doses of antipsychotics and length of hospital stay. Node strength was stable (CS(cor = 0.7) = 0.75). No clear pattern emerged among other lifestyle behaviors and health outcomes.
This study offers insights into the interrelatedness of lifestyle behaviors and health outcomes. Addressing sleep problems could enhance QoL and potentially influence other health outcomes. Psychological and physical QoL were also strongly associated, emphasizing the importance of perceived well-being in health outcomes. Future research could explore causal pathways to identify treatment targets to improve care.
不健康的生活方式行为在精神疾病患者中普遍存在，影响着他们的身心健康。大多数研究都集中在生活方式行为的孤立影响上，而这些行为与健康结果之间的相互联系尚未得到探索。本研究旨在探讨这些关系，并确定网络中联系最紧密的生活方式行为或健康结果。
我们对423名接受常规护理的住院精神疾病患者进行了一项横断面研究。通过问卷调查和常规数据评估生活方式行为、身心健康结果。估计了高斯图形模型，并计算了强度中心性以识别最具影响力的节点。
平均年龄为55.5岁，42%为女性，41%被诊断为精神分裂症。心理和生理生活质量（QoL）、夜间睡眠问题和总体睡眠质量是联系最紧密的节点。睡眠与生理生活质量密切相关。此外，健康食物摄入量与胆固醇比率之间存在负相关，抗精神病药物每日剂量与住院时间之间存在正相关。节点强度稳定（CS（cor = 0.7） = 0.75）。其他生活方式行为和健康结果之间未出现明显模式。
本研究为生活方式行为与健康结果的相互关系提供了见解。解决睡眠问题可以提高生活质量，并可能影响其他健康结果。心理和生理生活质量也密切相关，强调了感知幸福感在健康结果中的重要性。未来的研究可以探索因果途径，以确定改善护理的治疗靶点。
