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风险分析指标可预测初次全髋关节置换术后的30天假体周围骨折。

The risk analysis index predicts 30-day periprosthetic fracture following primary total hip arthroplasty.

作者信息

Sasaki Jared, Koltenyuk Victor, Albert Staton, Salehi Hirmand, Sambare Tanmaya D, Andrawis John

机构信息

School of Medicine, New York Medical College, United States.

Department of Orthopedic Surgery, Harbor-UCLA Medical Center, United States.

出版信息

J Orthop. 2025 Mar 15;69:112-116. doi: 10.1016/j.jor.2025.03.018. eCollection 2025 Nov.

Abstract

INTRODUCTION

As the number of patients requiring total hip arthroplasty (THA) continues to increase, it is critical to develop tools that predict postoperative periprosthetic fracture (PPF). One way to risk stratify patients undergoing THA is using a frailty score. Recently, the Risk Analysis Index (RAI) has emerged as a potentially more accurate marker of frailty and predictor of postoperative complications following spine surgery. Our study aims to assess the association between frailty, as rated by RAI, and PPF within 30 days following primary THA.

METHODS

The ACS NSQIP database was queried from the years 2015-2020 analyzing patients who underwent primary THA. The RAI scored patients on a scale from 0 to 81 and grouped them into four categories based on their frailty score: robust, normal, frail, and severely frail. Multivariate analysis was performed, controlling for age, female sex, American Society of Anesthesiologists (ASA) score, and tobacco smoking, with the primary outcome being PPF within 30 days of surgery.

RESULTS

A total of 186,756 patients were included in this study- 372 (0.2 %) of which had PPFs within the 30-day postoperative period. Increasing frailty, as measured by RAI, was a significant predictor of PPF following primary THA in normal, frail, and severely frail patients. Female sex and ASA status also showed increased risk of PPF. Furthermore, each additional unit on the RAI scale increased the odds of PPF by 7.5 %.

DISCUSSION

Frailty has been identified as a predictor of adverse postoperative outcomes in patients undergoing THA, however, this study is the first to find a significant association between frailty and PPF within 30 days of THA. Incorporating frailty assessment into preoperative discussions may aid surgeons in risk stratification, inform surgical decision-making, and enhance the effectiveness of postoperative monitoring following THA.

摘要

引言

随着需要进行全髋关节置换术(THA)的患者数量持续增加,开发能够预测术后假体周围骨折(PPF)的工具至关重要。对接受THA的患者进行风险分层的一种方法是使用衰弱评分。最近,风险分析指数(RAI)已成为一种可能更准确的衰弱标志物和脊柱手术后术后并发症的预测指标。我们的研究旨在评估RAI评定的衰弱与初次THA后30天内PPF之间的关联。

方法

查询2015 - 2020年的美国外科医师学会国家外科质量改进计划(ACS NSQIP)数据库,分析接受初次THA的患者。RAI对患者进行0至81分的评分,并根据其衰弱评分将他们分为四类:强健、正常、衰弱和严重衰弱。进行多变量分析,控制年龄、女性性别、美国麻醉医师协会(ASA)评分和吸烟情况,主要结局是术后30天内的PPF。

结果

本研究共纳入186,756例患者,其中372例(0.2%)在术后30天内发生PPF。在正常、衰弱和严重衰弱的患者中,通过RAI测量的衰弱程度增加是初次THA后PPF的显著预测指标。女性性别和ASA状态也显示出PPF风险增加。此外,RAI量表上每增加一个单位,PPF的几率增加7.5%。

讨论

衰弱已被确定为接受THA患者术后不良结局的预测指标,然而,本研究是首次发现衰弱与THA后30天内PPF之间存在显著关联。将衰弱评估纳入术前讨论可能有助于外科医生进行风险分层、为手术决策提供信息,并提高THA术后监测的有效性。

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