From the Department of Orthopaedic Surgery, Cleveland Clinic Foundation, Cleveland, OH.
J Am Acad Orthop Surg. 2024 Jul 1;32(13):e634-e641. doi: 10.5435/JAAOS-D-23-00936. Epub 2024 Apr 2.
Although the 5-factor modified frailty index (mFI-5) has been shown to be an independent predictor of complications after primary total hip arthroplasty (THA), its predictive value has not been evaluated in the setting of hip fracture. We therefore assessed the utility of mFI-5 score as an independent predictor of morbidity and mortality in patients who underwent THA or hemiarthroplasty for femoral neck fracture.
The American College of Surgeons National Surgical Quality Improvement database was queried for all patients with femoral neck fractures treated with THA or hemiarthroplasty between 2006 and 2020. A multivariate logistic regression analysis was done using mFI-5 as a predictor while controlling for baseline demographic and clinical variables.
In total, 45,185 patients (hemiarthroplasty: 37,645; THA: 7,540) were identified. For hemiarthroplasty patients, the mFI-5 strongly predicted risk of any complication (OR, 1.1; 95% CI, 1.1 to 1.2; P < 0.001), bleeding (OR, 1.2; 95% CI, 1.1 to 1.3; P < 0.001), and readmission (OR, 1.2; 95% CI, 1.1 to 1.3; P < 0.001). For THA patients, the mFI-5 was a strong predictor of any complication (OR, 1.2; 95% CI, 1.0 to 1.3; P = 0.023), pneumonia (OR, 1.4; 95% CI, 1.0 to 2.0; P = 0.047), and readmission (OR, 1.3; 95% CI, 1.1 to 1.6; P = 0.004).
The mFI-5 is an independent predictor of morbidity and complications after hemiarthroplasty and THA for femoral neck fracture. Importantly, readmission risk was predicted by the mFI-5. The mFI-5 may present a valuable clinical tool for assessment of high-risk patients who might require additional resources and specialized care after femoral neck fracture.
虽然五因素修正衰弱指数(mFI-5)已被证明是初次全髋关节置换术(THA)后并发症的独立预测因素,但在髋部骨折的情况下,其预测价值尚未得到评估。因此,我们评估了 mFI-5 评分作为预测接受 THA 或人工股骨头置换术治疗股骨颈骨折患者发病率和死亡率的独立指标的效用。
2006 年至 2020 年期间,美国外科医师学会国家手术质量改进数据库(American College of Surgeons National Surgical Quality Improvement database)对所有接受股骨颈骨折 THA 或人工股骨头置换术治疗的患者进行了查询。使用 mFI-5 作为预测因子进行多变量逻辑回归分析,同时控制基线人口统计学和临床变量。
共纳入 45185 例患者(人工股骨头置换术:37645 例;THA:7540 例)。对于人工股骨头置换术患者,mFI-5 强烈预测任何并发症的风险(OR,1.1;95%CI,1.1 至 1.2;P<0.001)、出血(OR,1.2;95%CI,1.1 至 1.3;P<0.001)和再入院(OR,1.2;95%CI,1.1 至 1.3;P<0.001)。对于 THA 患者,mFI-5 是任何并发症(OR,1.2;95%CI,1.0 至 1.3;P=0.023)、肺炎(OR,1.4;95%CI,1.0 至 2.0;P=0.047)和再入院(OR,1.3;95%CI,1.1 至 1.6;P=0.004)的强烈预测因子。
mFI-5 是人工股骨头置换术和 THA 治疗股骨颈骨折后发病率和并发症的独立预测因子。重要的是,mFI-5 预测了再入院风险。mFI-5 可能为评估需要额外资源和专业护理的高危患者提供有价值的临床工具,这些患者可能在股骨颈骨折后需要这些资源和护理。