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Normolipemic activities of acrylophenone derivatives with antimicrotubular properties.

作者信息

Bard J M, Luyckx M, Brunet C, Cazin M, Fruchart J C, Clavey V, Lesieur I, Lesieur D, Delacourte A

出版信息

Methods Find Exp Clin Pharmacol. 1985 Apr;7(4):183-7.

PMID:4021650
Abstract

Acrylophenone derivatives with in vitro antimicrotubular activities very similar to those of colchicine were tested on Triton WR 1339-induced hyperlipidemia in rats. They exhibit high normolipemic activity on plasmatic apolipoproteins AI and B, contrasting with inactivity on plasmatic lipids and lipoproteins.

摘要

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