Horák J, Horák A, Lenghel A, Cuparencu B
Department of Pharmacology, Faculty of Medicine, University of Oradea, Romania.
Acta Physiol Hung. 1997;85(1):77-82.
Lormetazepam (N-methyllorazepam) administered intraperitoneally to rats rendered hyperlipidemic by Triton WR-1339 induced an elevation of blood glucose level at all investigated doses. It brought about significant reduction of serum total lipids, total cholesterol and triglycerides. The dose-response relationship was bell-shaped. However, it presented two peaks, differing from the responses to other benzodiazepines (BZD) which were characterized by only one peak.
