Dowlatshahi K, Lester E, Bibbo M, Johnson C
Laryngoscope. 1985 Aug;95(8):971-5. doi: 10.1288/00005537-198508000-00017.
The incidence of associated esophageal carcinoma (EC) among patients with upper aerodigestive tract malignancies is high. Esophageal brush cytology, as developed and evaluated as a screening device for early detection of EC among villagers of northeastern Iran, was employed to examine 56 clinic patients with known tumors of the upper aerodigestive tract on 106 occasions. Two asymptomatic EC were detected and are presented. The procedure was also used as an adjunct to endoscopy in order to monitor the response of tumors under treatment. Sensitivity of 40% and specificity of 90% were found and could be improved with more judicious application of the procedure. The use of this simple test for early detection of EC among this high risk subset of clinic patients is recommended.
上消化道恶性肿瘤患者中合并食管癌（EC）的发生率很高。食管刷检细胞学检查是在伊朗东北部农村地区开发并作为早期检测EC的筛查工具进行评估的，对56例已知患有上消化道肿瘤的临床患者进行了106次检查。检测到2例无症状的EC并进行了报告。该检查还用作内镜检查的辅助手段，以监测治疗中肿瘤的反应。发现其敏感性为40%，特异性为90%，更合理地应用该检查可能会提高其性能。建议使用这种简单的检查方法在这一高风险临床患者亚组中早期检测EC。
