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抗VEGF治疗的视网膜静脉阻塞患者的远程监测:一项初步研究。

Remote Monitoring of Patients with Retinal Vein Occlusions Treated with Anti-VEGF: A Pilot Study.

作者信息

Castellino Niccolò, Cappellani Francesco, Dammino Edoardo, Rubegni Giovanni, Scollo Davide, Russo Andrea, Avitabile Teresio, Longo Antonio

机构信息

Department of Ophthalmology, University of Catania, 95123 Catania, Italy.

Ophthalmology Unit, Department of Medicine, Surgery and Neurosciences, University of Siena, 51300 Siena, Italy.

出版信息

J Clin Med. 2025 Mar 28;14(7):2330. doi: 10.3390/jcm14072330.

DOI:10.3390/jcm14072330
PMID:40217781
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11989553/
Abstract

: To assess the feasibility and effectiveness of remote monitoring for patients with retinal vein occlusion (RVO) treated with intravitreal anti-VEGF injections. : A retrospective analysis was conducted at the Eye Clinic of the University of Catania. Thirty-four eyes of 34 patients with RVO were included for a 12-month follow-up period. After a comprehensive baseline ophthalmic examination, the patients received a loading treatment consisting of three monthly intravitreal injections of anti-VEGF, followed by monthly or bimonthly remote follow-up visits at peripheral centers. Optical coherence tomography (OCT) images and clinical data were shared online with our eye clinic for remote evaluations. Data on hospital and peripheral center visits, intravitreal injections, and OCT scans were collected and analyzed. : The patients had an average of 5.71 ± 1.14 visits to peripheral centers and 2.1 ± 0.8 visits to our center for fluorescein angiography. The mean number of injections was 5.26 ± 1.29 and the mean improvement in best-corrected visual acuity (BCVA) was 11.47 ± 5.56 letters. Remote OCT evaluations accounted for 194 scans, there was a high agreement between two expert in-hospital examinators (Cohen's κ = 0.927) with only 14 cases requiring hospital visits for inconclusive results. : Remote monitoring for RVO patients significantly reduced hospital admissions for follow-up visits, reducing the clinical burden on medical staff, patients, and caregivers, while maintaining reliable patient assessments.

摘要

评估玻璃体腔内注射抗血管内皮生长因子(VEGF)治疗的视网膜静脉阻塞(RVO)患者进行远程监测的可行性和有效性。

在卡塔尼亚大学眼科诊所进行了一项回顾性分析。纳入34例RVO患者的34只眼,进行为期12个月的随访。在进行全面的基线眼科检查后,患者接受了负荷治疗,包括每月3次玻璃体腔内注射抗VEGF,随后在周边中心进行每月或每两个月一次的远程随访。光学相干断层扫描(OCT)图像和临床数据通过网络与我们的眼科诊所共享,以便进行远程评估。收集并分析了关于医院和周边中心就诊、玻璃体腔内注射以及OCT扫描的数据。

患者平均到周边中心就诊5.71±1.14次,到我们中心进行荧光素血管造影检查2.1±0.8次。平均注射次数为5.26±1.29次,最佳矫正视力(BCVA)平均提高11.47±5.56个字母。远程OCT评估共进行了194次扫描,两名医院专家检查者之间的一致性很高(Cohen's κ = 0.927),只有14例因结果不明确需要到医院就诊。

对RVO患者进行远程监测显著减少了随访的住院次数,减轻了医护人员、患者及其护理人员的临床负担,同时保持了对患者可靠的评估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bab/11989553/3a13e6a64d2b/jcm-14-02330-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bab/11989553/673551042673/jcm-14-02330-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bab/11989553/3a13e6a64d2b/jcm-14-02330-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bab/11989553/673551042673/jcm-14-02330-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bab/11989553/3a13e6a64d2b/jcm-14-02330-g002.jpg

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本文引用的文献

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Retinal Vein Occlusion-Background Knowledge and Foreground Knowledge Prospects-A Review.视网膜静脉阻塞——背景知识与前沿知识展望——综述
J Clin Med. 2024 Jul 5;13(13):3950. doi: 10.3390/jcm13133950.
2
Optimizing open-angle glaucoma risk assessment in patients with retinal vein occlusions.优化视网膜静脉阻塞患者的开角型青光眼风险评估。
Eye (Lond). 2024 Oct;38(15):2985-2991. doi: 10.1038/s41433-024-03205-y. Epub 2024 Jul 9.
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Intravitreal Anti-Vascular Endothelial Growth Factor Therapies for Retinal Disorders.用于视网膜疾病的玻璃体内抗血管内皮生长因子疗法
Pharmaceuticals (Basel). 2023 Aug 11;16(8):1140. doi: 10.3390/ph16081140.
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Impact of Routinely Performed Optical Coherence Tomography Examinations on Quality of Life in Patients with Retinal Diseases-Results from the ALBATROS Data Collection.常规光学相干断层扫描检查对视网膜疾病患者生活质量的影响——来自ALBATROS数据收集的结果
J Clin Med. 2023 Jun 7;12(12):3881. doi: 10.3390/jcm12123881.
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Transformation of chronic disease management: Before and after the COVID-19 outbreak.慢性病管理的转变:新冠疫情前后。
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Glaucoma and Telemedicine.青光眼与远程医疗
J Glaucoma. 2023 May 1;32(5):327-332. doi: 10.1097/IJG.0000000000002200. Epub 2023 Feb 28.
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Applications and Current Medico-Legal Challenges of Telemedicine in Ophthalmology.远程医疗在眼科的应用及当前医学法律挑战
Int J Environ Res Public Health. 2022 May 5;19(9):5614. doi: 10.3390/ijerph19095614.
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Retinal vein occlusion (RVO) guideline: executive summary.视网膜静脉阻塞(RVO)指南:执行摘要。
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Telemedicine for the Diagnosis and Management of Age-Related Macular Degeneration: A Review.远程医疗用于年龄相关性黄斑变性的诊断与管理:综述
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