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开角型青光眼和其他视神经萎缩患者接受全黄斑阈下二极管微脉冲激光(SDM)治疗后,通过标准自动视野计测量视野改善情况

Visual Field Improvement by Standardized Automated Perimetry Following Panmacular Subthreshold Diode Micropulse Laser (SDM) in Open-Angle Glaucoma and Other Optic Atrophies.

作者信息

Luttrull Jeffrey K, Bhavan Sathy V

机构信息

Ventura County Retina Vitreous Medical Group, 3160 Telegraph Rd., Suite 230, Ventura, CA 93003, USA.

出版信息

Diagnostics (Basel). 2025 Apr 2;15(7):912. doi: 10.3390/diagnostics15070912.

DOI:10.3390/diagnostics15070912
PMID:40218262
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11989141/
Abstract

To assess the effect of subthreshold diode micropulse laser (SDM) on visual fields (VF) by standardized automated perimetry (SAP) in open-angle glaucoma (OAG) and other non-glaucomatous optic atrophies (OA). The electronic medical records in a vitreoretinal practice were searched to identify the cohort of eyes with OAG and OA that underwent SAP before and after the initial SDM meeting study inclusion and exclusion criteria. Recorded data included mean deviation (MD), mean sensitivity (MS), and pattern standard deviation (PSD) before and after treatment. A total of 55 eyes of 29 patients, 17 female, aged 62-89 years (avg. 76), with 48 eyes having OAG and 7 with OA, were included in the study. All SAP tests were performed the same day prior to the first SDM treatment, and the postop SAP within one month post-treatment. There were three groups: 36 total treated eyes, 14 treated simultaneously in both eyes prior to repeat SAP, and 22 treated in one eye prior to repeat SAP, along with 19 untreated fellow eye controls. Following SDM, MD and MS were significantly improved in all treated eyes and unilaterally treated eyes ( range 1.0 × 10 to 7.02 × 10). Untreated fellow eyes were also significantly improved ( = 0.03 for both MD and MS), but the MD and MS improvements in the treated eyes were significantly greater than untreated fellow eyes ( = 0.016 for both MD and MS). Panmacular SDM significantly improved VF by SAP in eyes with OAG and OA. This finding has important implications for management in both conditions.

摘要

通过标准自动视野计(SAP)评估阈下二极管微脉冲激光(SDM)对开角型青光眼(OAG)和其他非青光眼性视神经萎缩(OA)患者视野(VF)的影响。检索玻璃体视网膜科的电子病历,以确定符合研究纳入和排除标准、在首次SDM治疗前后接受过SAP检查的OAG和OA患者队列。记录的数据包括治疗前后的平均偏差(MD)、平均敏感度(MS)和模式标准差(PSD)。该研究共纳入29例患者的55只眼,其中女性17例,年龄62 - 89岁(平均76岁),48只眼患有OAG,7只眼患有OA。所有SAP检查均在首次SDM治疗前的同一天进行,术后SAP在治疗后1个月内进行。分为三组:36只接受治疗的眼,其中14只在重复SAP检查前双眼同时接受治疗,22只在重复SAP检查前单眼接受治疗,以及19只未治疗的对侧眼作为对照。SDM治疗后,所有接受治疗的眼和单眼治疗的眼的MD和MS均显著改善(范围为1.0×10至7.02×10)。未治疗的对侧眼也有显著改善(MD和MS均为P = 0.03),但治疗眼的MD和MS改善程度显著大于未治疗的对侧眼(MD和MS均为P = 0.016)。全黄斑区SDM通过SAP显著改善了OAG和OA患者的视野。这一发现对这两种疾病的治疗具有重要意义。

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本文引用的文献

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Subthreshold Micropulse Laser Modulates Retinal Neuroinflammatory Biomarkers in Diabetic Macular Edema.
阈下微脉冲激光调节糖尿病性黄斑水肿中的视网膜神经炎症生物标志物。
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CHANGES OF AQUEOUS HUMOR MÜLLER CELLS' BIOMARKERS IN HUMAN PATIENTS AFFECTED BY DIABETIC MACULAR EDEMA AFTER SUBTHRESHOLD MICROPULSE LASER TREATMENT.经阈下微脉冲激光治疗后,糖尿病性黄斑水肿患者房水Müller 细胞生物标志物的变化。
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