Kim Min-Jung, Lee Kyung Mi, Hur Sung-Pyo, Choi Cheol Young, Kim Jun-Hwan
Department of Marine Life Science, Jeju National University, Jeju 63243, Republic of Korea.
Aquaculture Industry Division, West Sea Fisheries Research Institute, National Institute of Fisheries Science, Incheon 22383, Republic of Korea.
Animals (Basel). 2025 Mar 24;15(7):932. doi: 10.3390/ani15070932.
Lead (Pb) is a non-essential toxic metal that accumulates in aquatic environments, negatively impacting fish health. This study evaluated the acute toxicity of Pb in starry flounders (). Fish (41 ± 8.1 g, 14 ± 0.9 cm) were exposed to Pb concentrations of 0, 10, 20, 40, 80, 160, 320, and 640 mg Pb/L for 96 h. The lethal concentration (96 h LC) was determined to be 227 mg Pb/L. Hematological analysis showed significant decreases in RBC counts, hemoglobin, and hematocrit, while MCH and MCHC increased at ≥160 mg Pb/L. Plasma calcium levels significantly decreased following Pb exposure, and AST activity was reduced. These findings suggest that acute waterborne Pb exposure adversely affects survival, hematological parameters, and plasma components in , providing insight into Pb toxicity in aquatic organisms.
铅（Pb）是一种非必需的有毒金属，会在水生环境中蓄积，对鱼类健康产生负面影响。本研究评估了铅对星斑川鲽（）的急性毒性。将鱼（41±8.1克，14±0.9厘米）暴露于浓度为0、10、20、40、80、160、320和640毫克铅/升的铅环境中96小时。测定致死浓度（96小时LC）为227毫克铅/升。血液学分析显示，红细胞计数、血红蛋白和血细胞比容显著降低，而当铅浓度≥160毫克铅/升时，平均红细胞血红蛋白含量（MCH）和平均红细胞血红蛋白浓度（MCHC）增加。铅暴露后血浆钙水平显著降低，天冬氨酸转氨酶（AST）活性降低。这些发现表明，急性水体铅暴露会对星斑川鲽的生存、血液学参数和血浆成分产生不利影响，为了解铅在水生生物中的毒性提供了依据。
