Kujawa M, Macholz R M, Plass R, Knoll R, Engst R
Nahrung. 1985;29(4):405-10. doi: 10.1002/food.19850290426.
DDT orally given to rats is converted into DDD by reductive dechlorination in the liver within 30 min. 6 h after a single application of 10 mg DDT per rat a quantity of 60 mg DDD/kg was indicated in the liver. DDT is stored in the adrenal glands; in the other organs an equilibrium comes up obviously, even with further application. The quantitative ratios are reported. Information on the experimental details of DDT determination and--anticipatory to the following publications--on the analysis of the most relevant metabolites is given.
给大鼠口服滴滴涕后,30分钟内在肝脏中通过还原脱氯作用转化为滴滴滴。每只大鼠单次施用10毫克滴滴涕6小时后,肝脏中显示出60毫克滴滴滴/千克的量。滴滴涕储存在肾上腺中;在其他器官中,即使进一步施用,也明显达到平衡。报告了定量比率。给出了滴滴涕测定实验细节的信息,以及(作为后续出版物的预告)最相关代谢物分析的信息。