Jiménez-Maldonado Alberto, Antunes Barbara Moura, Reyes Rubén Avilés, Rentería Iván, Blanco-Salazar Alberto, Moncada-Jiménez José, Guevara Isaac A Chávez, Machado-Parra Juan Pablo, Lira Fabio Santos, Rossi Fabrício Eduardo
Facultad de Deportes Campus Ensenada, Universidad Autónoma de Baja California (UABC), Ensenada, BC, Mexico.
Exercise and Immunometabolism Research Group, Department of Physical Education, São Paulo State University (UNESP), Presidente Prudente, SP, Brazil.
Physiol Behav. 2025 Jun 1;295:114916. doi: 10.1016/j.physbeh.2025.114916. Epub 2025 Apr 11.
High-intensity circuit training (HICT) is an exercise modality converging aerobic and resistance exercises executed at high-intensity interspersed by recovery periods. During the HICT, the participants use their body weight as resistance. The impact of HICT on metabolic and cardiovascular markers has been reported, the effect of HICT on brain function remains unknown. The current study was focus to evaluate the impact of 24 HICT sessions on the serum BDNF (sBDNF) levels and cognition skills in young adults. Fifteen college students (22.1 ± 5.3 yr.) were randomly assigned to a control (CTRL) (n = 7) or a HICT (n = 8) group. The CTRL group continued their daily activities without restricting their physical activities, the HICT group carried out 24 HICT sessions. The sBDNF levels of all participants pre- and post-HICT intervention were determined by ELISA method. Visual memory, verbal memory, semantic verbal fluency, and attention were evaluated with specific neuropsychological tests. The heart rate variability (HRV) was recorded at rest in the supine position (5 min) for both groups at the beginning of the HICT program and 24 h after the intervention. The sBDNF levels increased in both groups at the end of the study (p < 0.0001). Visual memory (delayed recall) and long-term verbal memory significantly improved after HICT (p < 0.01). The HRV was unchanged by HICT. In conclusion, HICT might be a feasible method to improve cognition abilities in active young adults, and it is becoming a good option for college students since the intervention did not induce physiological stress in the participants.
高强度循环训练（HICT）是一种将有氧运动和阻力运动相结合的运动方式，以高强度进行，中间穿插恢复期。在HICT期间，参与者以自身体重作为阻力。已有研究报道了HICT对代谢和心血管指标的影响，但HICT对脑功能的影响尚不清楚。本研究旨在评估24次HICT训练对年轻成年人血清脑源性神经营养因子（sBDNF）水平和认知技能的影响。15名大学生（22.1±5.3岁）被随机分为对照组（CTRL）（n = 7）或HICT组（n = 8）。CTRL组继续其日常活动，不限制身体活动，HICT组进行24次HICT训练。采用酶联免疫吸附测定法（ELISA）测定所有参与者在HICT干预前后的sBDNF水平。通过特定的神经心理学测试评估视觉记忆、言语记忆、语义言语流畅性和注意力。在HICT计划开始时和干预后24小时，两组均在仰卧位静息状态下记录心率变异性（HRV）（5分钟）。研究结束时，两组的sBDNF水平均升高（p < 0.0001）。HICT后视觉记忆（延迟回忆）和长期言语记忆显著改善（p < 0.01）。HICT对HRV没有影响。总之，HICT可能是提高活跃年轻成年人认知能力的一种可行方法，并且由于该干预未在参与者中引起生理应激，它正成为大学生的一个不错选择。
