Gu Guoqiang, Zhou Yaqing, Zhang Ying, Cui Wei
Department of Cardiology, The Second Hospital of Hebei Medical University, No. 215, He Ping Xi Road, Shijiazhuang, 05000, China.
BMC Psychiatry. 2016 Jul 22;16:259. doi: 10.1186/s12888-016-0972-9.
Evidence suggests that coronary heart disease (CHD) is associated with increased anxiety and a high incidence of comorbid anxiety and depression. However, the association between percutaneous coronary intervention (PCI) and comorbid anxiety and depression has not been previously investigated. This study aims to determine the relationship between PCI and anxiety and depression symptoms in CHD patients in terms of the occurrence, prone factors, and long-term outcomes of CHD.
One hundred seventy CHD patients who underwent PCI treatment between September 2013 and February 2014 at the Second Hospital of Hebei Medical University were randomly selected. All patients independently completed the Hospital Anxiety and Depression Scale (HADS) and a preoperative questionnaire; they also provided details regarding their PCI-related concerns one day before PCI, as well as one day and one, three, six, and 12 months after PCI.
PCI treatment was significantly associated with the symptoms of anxiety, depression, affective disorders, and comorbid anxiety and depression (χ(2) = 90.18, 54.45, 101.59, 64.83; p < 0.01) at each follow-up time point. Moreover, PCI treatment was linearly correlated with each of these psychological issues (p < 0.01).
The prevalence of anxiety, depression, and comorbid anxiety and depression symptoms significantly increases one day before and after PCI treatment; however, the incidence of these psychological issues significantly decreases with time following PCI. A low level of education, apprehension with regard to nursing quality, potential cardiac dysfunction, surgery sequelae, and surgery failure are also associated with a high prevalence of anxiety and depression symptoms.
有证据表明，冠心病（CHD）与焦虑增加以及焦虑和抑郁共病的高发生率相关。然而，经皮冠状动脉介入治疗（PCI）与焦虑和抑郁共病之间的关联此前尚未得到研究。本研究旨在从冠心病的发生、易感因素和长期预后方面确定PCI与冠心病患者焦虑和抑郁症状之间的关系。
随机选取2013年9月至2014年2月在河北医科大学第二医院接受PCI治疗的170例冠心病患者。所有患者均独立完成医院焦虑抑郁量表（HADS）和术前问卷；他们还在PCI前一天以及PCI后一天、1个月、3个月、6个月和12个月提供了有关其PCI相关担忧的详细信息。
在每个随访时间点，PCI治疗与焦虑、抑郁、情感障碍以及焦虑和抑郁共病症状显著相关（χ(2)=90.18、54.45、101.59、64.83；p<0.01）。此外，PCI治疗与这些心理问题均呈线性相关（p<0.01）。
PCI治疗前后一天，焦虑、抑郁以及焦虑和抑郁共病症状的患病率显著增加；然而，这些心理问题的发生率在PCI后随时间显著降低。低教育水平、对护理质量的担忧、潜在的心功能不全、手术后遗症和手术失败也与焦虑和抑郁症状的高患病率相关。
