Plesko I, Somogyi J, Dimitrova E, Havránková M, Kiss J
Neoplasma. 1985;32(3):273-84.
The trends of age-adjusted incidence rates of malignant skin melanoma in Slovakia from 1968 to 1977 showed important increase with an annual increment of 5.8% in males and 3.2% in females. The mortality rates during this period remained lower and their increase was less expressed. The study of geographic patterns of incidence revealed great variation with highest rates in urban districts. A marked predominance of the primary lesions on trunk in males and on lower limbs in females was observed. The differences in anatomic distribution are demonstrated also in age-specific incidence rates of malignant skin melanoma by main subsites. Intermittent overexposures to the sunlight in connection with rising standard of life and leisure seem to be the most suitable explanation for the rise and subsite distribution and dynamics, as well as the geographic patterns and international position of incidence rates of malignant skin melanoma in this country.
1968年至1977年斯洛伐克恶性皮肤黑色素瘤年龄调整发病率趋势显示,男性年增长率为5.8%,女性为3.2%,呈显著上升。在此期间死亡率较低,上升幅度较小。发病率地理模式研究显示差异很大,城市地区发病率最高。观察到男性原发性皮损主要位于躯干,女性主要位于下肢。主要亚部位的恶性皮肤黑色素瘤年龄别发病率也显示了解剖分布差异。随着生活水平和休闲标准的提高,间歇性过度暴露于阳光下似乎是该国恶性皮肤黑色素瘤发病率上升、亚部位分布和动态变化,以及地理模式和国际发病率状况的最合适解释。