Ni Jie, Yang Hang, Li Xiaojun, Chen Fei, Lu Wei, Ye Xinjian, Cai Xia, He Fuming
Key Laboratory of Oral Biomedical Research of Zhejiang Province, School of Stomatology, Stomatology Hospital, Zhejiang Provincial Clinical Research Center for Oral Diseases, Cancer Center of Zhejiang University, Engineering Research Center of Oral Biomaterials and Devices of Zhejiang Province, Zhejiang University School of Medicine, Hangzhou, 310000, China.
Odontology. 2025 Apr 13. doi: 10.1007/s10266-025-01100-w.
To evaluate the clinical efficacy and influencing factors of the tunnel flap (TUN) combined with de-epithelialized connective tissue graft (DCTG) in the treatment of gingival recession (GR) from patient- and site-specific perspectives. Patients treated with the TUN + DCTG technique for GR between August 2020 and December 2023 were included. Baseline and follow-up periodontal measurements were recorded, including gingival recession depth (GRD), keratinized gingival width (KGW), and clinical attachment loss (CAL). Paired sample t-test was performed to assess the clinical efficacy. Moreover, primary outcome metrics, such as complete root coverage rate (CRC), mean root coverage rate (MRC), root coverage esthetic score (RES), and patient satisfaction, were calculated. Patient- and site-specific influencing factors were analyzed using a generalized linear mixed model regression (GLMM). A total of 34 patients with 201 affected teeth were included, comprising 78 cases of Cairo RT1, 86 of RT2, and 37 of RT3. Significant clinical improvements were observed over an average follow-up of 11.97 ± 4.11 months, including reductions in GRD (from 2.13 ± 1.14 mm to 0.48 ± 0.73 mm, P < 0.001) and CAL (from 3.22 ± 1.16 mm to 1.64 ± 0.90 mm, P < 0.001) and increases in KGW (from 2.58 ± 1.28 mm to 3.72 ± 1.66 mm, P < 0.001), with a CRC of 59.2% and MRC of 77.26% ± 33.48%. The mean RES was 8.21 ± 1.74, with 83.3% of patients reporting an improved quality of life. GLMM identified recession type, age, and tooth arch as predictable factors for clinical outcomes (P < 0.001). Within its limitations, this study suggests that the TUN + DCTG technique is a promising approach for managing GR, yielding favorable clinical and aesthetic outcomes. Clinical decision-making for GR treatment should consider a range of influencing factors to optimize individualized patient care.Clinical relevance: The TUN + DCTG technique is a reliable and effective option for GR treatment, providing consistent clinical and aesthetic benefits. Understanding predictive factors enables clinicians to tailor treatment strategies, improving success rates and patient satisfaction.
从患者和位点特异性角度评估隧道瓣(TUN)联合去上皮结缔组织移植(DCTG)治疗牙龈退缩(GR)的临床疗效及影响因素。纳入2020年8月至2023年12月期间采用TUN+DCTG技术治疗GR的患者。记录基线和随访期的牙周测量指标,包括牙龈退缩深度(GRD)、角化龈宽度(KGW)和临床附着丧失(CAL)。采用配对样本t检验评估临床疗效。此外,计算主要结局指标,如完全牙根覆盖率(CRC)、平均牙根覆盖率(MRC)、牙根覆盖美学评分(RES)和患者满意度。使用广义线性混合模型回归(GLMM)分析患者和位点特异性影响因素。共纳入34例患者的201颗患牙,其中开罗RT1型78例,RT2型86例,RT3型37例。平均随访11.97±4.11个月时观察到显著的临床改善,包括GRD降低(从2.13±1.14mm降至0.48±0.73mm,P<0.001)和CAL降低(从3.22±1.16mm降至1.64±0.90mm,P<0.001)以及KGW增加(从2.58±1.28mm增至3.72±1.66mm,P<0.001),CRC为59.2%,MRC为77.26%±33.48%。平均RES为8.21±1.74,83.3%的患者报告生活质量有所改善。GLMM确定退缩类型、年龄和牙弓为临床结局的可预测因素(P<0.001)。在其局限性范围内,本研究表明TUN+DCTG技术是治疗GR的一种有前景的方法,可产生良好的临床和美学效果。GR治疗的临床决策应考虑一系列影响因素,以优化个体化患者护理。临床相关性:TUN+DCTG技术是GR治疗的可靠且有效的选择,可提供一致的临床和美学益处。了解预测因素使临床医生能够调整治疗策略,提高成功率和患者满意度。