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隧道技术(TUN)与冠向复位瓣(CAF)治疗多处牙龈退缩缺损的疗效比较:一项荟萃分析

Efficacy of Tunnel Technique (TUN) versus Coronally Advanced Flap (CAF) in the Management of Multiple Gingival Recession Defects: A Meta-Analysis.

作者信息

Mayta-Tovalino Frank, Barboza Joshuan J, Pasupuleti Vinay, Hernandez Adrian V

机构信息

Unidad de Revisiones Sistemáticas y Meta-Análisis (URSIGET), Vicerrectorado de Investigación, Universidad San Ignacio de Loyola, Lima, Peru.

Vicerrectorado de Investigación, Universidad Norbert Wiener, Lima, Peru.

出版信息

Int J Dent. 2023 Apr 6;2023:8671484. doi: 10.1155/2023/8671484. eCollection 2023.

Abstract

OBJECTIVE

We systematically assessed the efficacy of tunnel technique (TUN) vs. coronally advanced flap (CAF) in the management of multiple gingival recession defects in adults.

METHODS

Five databases were searched until September 2021 for randomized controlled trials (RCTs) assessing TUN vs. CAF; grafts of interest were acellular dermal matrix (ADM) and connective tissue graft (CTG). Primary outcomes were root coverage (RC) and complete root coverage (CRC). Secondary outcomes were clinical attachment level (CAL), keratinized tissue width (KTW), probing depth (PD), and recession coverage (REC). Effect measures were risk ratio (RR) or mean difference (MD) with their confidence intervals (95% CI). Inverse variance methods and random-effects model meta-analyses were used. Subgroup analyses by the type of graft were performed. Quality of evidence was assessed using GRADE methodology.

RESULTS

Five RCTs ( = 173) were included, with a follow-up of 6 months for all outcomes. In comparison to CAF, TUN did not significantly reduce CRC (RR 0.65; 95% CI 0.002-176.7; = 0.51) and did not increase RC (MD 0.99%; 95% CI -6.7 to 8.6; = 0.80). In comparison to CAF, TUN showed no significant reduction of secondary outcomes. Subgroup analyses by type of graft showed no differences in comparison to primary analyses for primary and secondary outcomes. Three RCTs had a high risk of bias, and five RCTs had very low quality of evidence for all outcomes.

CONCLUSIONS

In adults with gingival recessions, TUN had similar primary and secondary outcomes in comparison with CAF. Subgroup analyses by the type of graft did not affect main conclusions. More RCTs with better design are needed to further characterize the effects of TUN vs. CAF in the treatment of multiple gingival recession defects.

摘要

目的

我们系统评估了隧道技术(TUN)与冠向推进瓣(CAF)在治疗成人多处牙龈退缩缺损中的疗效。

方法

检索了五个数据库至2021年9月,以查找评估TUN与CAF的随机对照试验(RCT);感兴趣的移植物为脱细胞真皮基质(ADM)和结缔组织移植物(CTG)。主要结局为牙根覆盖(RC)和完全牙根覆盖(CRC)。次要结局为临床附着水平(CAL)、角化组织宽度(KTW)、探诊深度(PD)和退缩覆盖(REC)。效应量为风险比(RR)或均值差(MD)及其置信区间(95%CI)。采用逆方差法和随机效应模型进行荟萃分析。按移植物类型进行亚组分析。使用GRADE方法评估证据质量。

结果

纳入了五项RCT(n = 173),所有结局均随访6个月。与CAF相比,TUN并未显著降低CRC(RR 0.65;95%CI 0.002 - 176.7;P = 0.51),也未增加RC(MD 0.99%;95%CI -6.7至8.6;P = 0.80)。与CAF相比,TUN在次要结局方面未显示出显著降低。按移植物类型进行的亚组分析显示,与主要结局和次要结局的主要分析相比无差异。三项RCT存在高偏倚风险,五项RCT在所有结局方面证据质量都非常低。

结论

在患有牙龈退缩的成人中,与CAF相比,TUN的主要和次要结局相似。按移植物类型进行的亚组分析未影响主要结论。需要更多设计更好的RCT来进一步明确TUN与CAF在治疗多处牙龈退缩缺损中的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3ee3/10101741/3dfb593f983e/IJD2023-8671484.001.jpg

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