Suppr超能文献

腐胺在集胞藻6803中的摄取、积累及其致死性

Uptake and accumulation of putrescine and its lethality in Anacystis nidulans.

作者信息

Guarino L A, Cohen S S

出版信息

Proc Natl Acad Sci U S A. 1979 Jul;76(7):3184-8. doi: 10.1073/pnas.76.7.3184.

Abstract

The rate of uptake of putrescine by Anacystis nidulans has been shown to depend on the external pH and the extracellular concentration of putrescine. Accumulation of exogenous putrescine was also proportional to the concentration of putrescine in the medium, suggesting that putrescine uptake was not subject to cellular regulation. An equation was derived to test the hypothesis that putrescine accumulation was due to ion trapping. Comparison of the predicted and observed intracellular concentrations of putrescine under various conditions showed a close correlation in support of the hypothesis of ion trapping. Under conditions leading to cell death (e.g., 150 microM putrescine, pH 9.8), the correlation did not hold as a result of leakage of accumulated putrescine.

摘要

已证明集胞藻摄取腐胺的速率取决于外部pH值和腐胺的细胞外浓度。外源腐胺的积累也与培养基中腐胺的浓度成正比,这表明腐胺的摄取不受细胞调节。推导了一个方程来检验腐胺积累是由于离子捕获这一假设。比较各种条件下预测的和观察到的细胞内腐胺浓度,结果显示出密切的相关性,支持了离子捕获的假设。在导致细胞死亡的条件下(例如,150微摩尔腐胺,pH 9.8),由于积累的腐胺泄漏,这种相关性不成立。

相似文献

2
Mechanism of toxicity of putrescine in Anacystis nidulans.腐胺对集胞藻6803的毒性作用机制。
Proc Natl Acad Sci U S A. 1979 Aug;76(8):3660-4. doi: 10.1073/pnas.76.8.3660.
3
An in vivo requirement for calcium in Photosystem II of Anacystis nidulans.集胞藻6803光系统II中钙的体内需求
Biochem Biophys Res Commun. 1982 Dec 31;109(4):1134-9. doi: 10.1016/0006-291x(82)91895-2.
8
Methylammonium transport in Anacystis nidulans R-2.集胞藻6803中甲基铵的转运
J Bacteriol. 1984 Oct;160(1):204-10. doi: 10.1128/jb.160.1.204-210.1984.
9
Polyamine transport in Aspergillus nidulans.构巢曲霉中的多胺转运
J Gen Microbiol. 1982 Mar;128(3):557-63. doi: 10.1099/00221287-128-3-557.

引用本文的文献

3
Polyamine uptake in carrot cell cultures.多胺在胡萝卜细胞培养物中的摄取。
Plant Physiol. 1987 Jun;84(2):374-80. doi: 10.1104/pp.84.2.374.
7
Mechanism of toxicity of putrescine in Anacystis nidulans.腐胺对集胞藻6803的毒性作用机制。
Proc Natl Acad Sci U S A. 1979 Aug;76(8):3660-4. doi: 10.1073/pnas.76.8.3660.

本文引用的文献

6
Substrate specificity of uptake of diamines in mouse brain slices.小鼠脑切片中二胺摄取的底物特异性。
Arch Biochem Biophys. 1974 Dec;165(2):539-47. doi: 10.1016/0003-9861(74)90280-x.
10
The proton electrochemical gradient in Escherichia coli cells.大肠杆菌细胞中的质子电化学梯度。
Eur J Biochem. 1976 Apr 1;63(2):533-41. doi: 10.1111/j.1432-1033.1976.tb10257.x.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验