Lim Peter Paul, Morisette Kayla, Keith Meredith, Hines Eric, Huntington Mark K
Department of Pediatrics, Division of Infectious Diseases, Avera McKennan University Health Center, Sioux Falls, USA.
Department of Pediatrics, Division of Infectious Diseases, University of South Dakota Sanford School of Medicine, Sioux Falls, USA.
Cureus. 2025 Mar 14;17(3):e80585. doi: 10.7759/cureus.80585. eCollection 2025 Mar.
Spinal phlegmon has rarely been reported in meningococcemia. Simultaneous polymicrobial infection has been occasionally reported as the etiology of meningitis. The development of a spinal phlegmon and optic neuritis complicated meningitis in a five-year-old male who presented with clinical sepsis and meningitis. () and herpes simplex virus 1 (HSV-1) were demonstrated in the cerebrospinal fluid. Investigation of potential immunocompromise revealed no identified deficit. Protracted antibiotics and antiviral therapy were completed with a favorable clinical outcome. This is potentially the first reported case of spinal phlegmon associated with meningococcal meningitis in an immunocompetent pediatric patient. It occurred in the clinical context of what appeared to be a simultaneous infection by and HSV-1.
脊髓蜂窝织炎在脑膜炎球菌血症中鲜有报道。同时发生的多重微生物感染偶尔被报道为脑膜炎的病因。一名五岁男性出现临床败血症和脑膜炎，并发脊髓蜂窝织炎和视神经炎。脑脊液中检测到（）和单纯疱疹病毒1型（HSV-1）。对潜在免疫功能低下的调查未发现明确缺陷。长期使用抗生素和抗病毒治疗取得了良好的临床效果。这可能是首例在免疫功能正常的儿科患者中报道的与脑膜炎球菌性脑膜炎相关的脊髓蜂窝织炎病例。它发生在看似同时感染（）和HSV-1的临床背景下。
