Orlović Zrinka, Rey-Ares Lucila, Viozzi María Florencia, Martins Rui, Villarreal Ramírez Juliana, Veiga Santiago, Connolly Mark P
Global Market Access Solutions SARL, Chardonne, Switzerland.
Faculty of Economics and Business, Department of Managerial Economics, University of Zagreb, Zagreb, Croatia.
J Health Econ Outcomes Res. 2025 Apr 9;12(1):129-137. doi: 10.36469/001c.133639. eCollection 2025.
Migraine is a prevalent, underdiagnosed, highly debilitating neurological condition that affects individuals' quality of life and often negatively influences normal daily activities. The study objective is to estimate the economic burden of migraine to the Argentine government by assessing the impact of the disease on tax revenue, absenteeism, and social support transfers. The analysis combines a cross-sectional model utilizing national demographic data and published migraine prevalence rates to estimate the annual burden for the entire migraine-affected cohort, and a longitudinal model assessing the average burden per individual from the age of 40, over a 20-year horizon. A fiscal framework based on generational accounting evaluated the impact of migraine on government finances. Sources of revenue such as direct and indirect taxes were weighted against elements of public expenditure (public sector absenteeism, healthcare expenses, and financial support) and compared with the general population. The effect of migraine on occupational outcomes was sourced from peer-reviewed publications, and costs were sourced from national databases. Results were reported as incremental fiscal consequences (2023 US dollars) and were discounted at 3% annually. The fiscal burden of migraine in Argentina was estimated to be 1237 million across the entire migraine population. Annually, 29% of government costs were due to public sector absenteeism, 39% related to healthcare costs, 19% to foregone direct and indirect tax revenue, and 12% to foregone corporation taxes. Additional government transfers represented a minor contribution to the overall fiscal impact of migraine in Argentina. The high rate of informal employment is likely to undermine disease burden estimates. Gender disparities were notable, with women bearing 76% of the burden, highlighting the need for gender-specific interventions. This study reveals a significant economic burden of migraine to the Argentinian government, primarily driven by absenteeism, healthcare costs, and foregone tax contributions. Targeted, gender-responsive healthcare and labor policies, especially for sectors with high informal employment, could help reduce these fiscal impacts.
偏头痛是一种常见但诊断不足、使人极度衰弱的神经系统疾病，会影响个人生活质量，并常常对正常日常活动产生负面影响。该研究的目的是通过评估该疾病对税收、旷工和社会支持转移的影响，来估算偏头痛给阿根廷政府带来的经济负担。该分析结合了一个横断面模型和一个纵向模型，横断面模型利用国家人口数据和已公布的偏头痛患病率来估算整个受偏头痛影响人群的年度负担，纵向模型则评估40岁起20年期间每个个体的平均负担。一个基于代际核算的财政框架评估了偏头痛对政府财政的影响。将直接税和间接税等收入来源与公共支出要素（公共部门旷工、医疗费用和财政支持）进行加权，并与普通人群进行比较。偏头痛对职业结果的影响来自同行评审出版物，成本则来自国家数据库。结果以增量财政后果（2023美元）报告，并按每年3%进行贴现。阿根廷偏头痛人群的财政负担估计为1.237亿美元。每年，29%的政府成本归因于公共部门旷工，39%与医疗成本相关，19%与直接和间接税收收入损失有关，12%与企业税收损失有关。额外的政府转移支付对阿根廷偏头痛的总体财政影响贡献较小。高比例的非正规就业可能会削弱疾病负担估计。性别差异显著，女性承担了76%的负担，这凸显了针对性别干预措施的必要性。这项研究揭示了偏头痛给阿根廷政府带来的巨大经济负担，主要由旷工、医疗成本和税收贡献损失驱动。有针对性的、对性别问题有敏感认识的医疗和劳动力政策，特别是针对非正规就业比例高的部门，有助于减少这些财政影响。
