Department of Strabismus & Pediatric Ophthalmology, Shenzhen Eye Hospital Affiliated to Jinan University, Shenzhen University of Medicine, Shenzhen, China.
National Engineering Research Center for Healthcare Devices, Guangzhou, China.
Cyberpsychol Behav Soc Netw. 2022 Oct;25(10):672-677. doi: 10.1089/cyber.2022.0162. Epub 2022 Aug 1.
To explore the relationship between binocular imbalance (BI) and the abnormal development of binocular refraction. BI data were collected by enrolling the first 1,000 adolescents and children aged 6-18 years in Shenzhen Eye Hospital from April 2020 to January 2021. In this cross-sectional study, the imbalance value (IV) did not show a statistical correlation with the spherical equivalent (SE) (oculus dexter [OD]: = 0.022, = 0.586; oculus sinister [OS]: = -0.021, = 0.606), and had little correlation with the uncorrected visual acuity (VA) (OD: = -0.084, = 0.039; OS: = -0.034, = 0.408). The proportion of binocular contrast imbalance (BCI) (the absolute value) maintained the highest level (from 54.42 to 79.17 percent) with the increase of bilateral SE difference in the four subcategories (binocular balance, monocular suppression, binocular rivalry, and BCI). From -100 to +100 of IV, the SE of the left eye tends to increase negatively when compared with the right eye (from -95 < IV ≦ -80, SE difference = -0.83 ± 1.58, to -20 < IV ≦ -10, SE difference = -0.14 ± 0.61; from 10 ≦ IV <20, SE difference = -0.05 ± 0.80, to 80 ≦ IV <95, SE difference = 1.48 ± 2.77). BI widely exists within the general pediatric population. The BI did not show significant correlation with the unilateral eye refractive state and the VA. However, the BI may be accompanied by imbalanced development of the eye refractive system. Furthermore, the SE of the dominant eye (from the prospective of BI) tends to be more negative than that of the opposite eye as the value increases. Clinical Trial Registration number: ChiCTR2100045457.
探讨双眼不平衡（BI）与双眼屈光异常的发展关系。本横断面研究通过招募 2020 年 4 月至 2021 年 1 月在深圳眼科学医院就诊的 1000 名 6-18 岁青少年和儿童，收集 BI 数据。不平衡值（IV）与球镜等效（SE）无统计学相关性（右眼： = 0.022， = 0.586；左眼： = -0.021， = 0.606），与未矫正视力（VA）相关性较小（右眼： = -0.084， = 0.039；左眼： = -0.034， = 0.408）。双眼对比不平衡（BCI）（绝对值）的比例随着双侧 SE 差值的增加而保持最高水平（在四个亚类中，从 54.42%至 79.17%）：双眼平衡、单眼抑制、双眼竞争和 BCI。在 IV 从-100 到+100 范围内，当左眼 IV 与右眼 IV 相比时，左眼 SE 呈负向趋势（从-95 < IV ≦ -80，SE 差异 = -0.83 ± 1.58，到-20 < IV ≦ -10，SE 差异 = -0.14 ± 0.61；从 10 ≦ IV <20，SE 差异 = -0.05 ± 0.80，到 80 ≦ IV <95，SE 差异 = 1.48 ± 2.77）。BI 在一般儿科人群中广泛存在。BI 与单侧眼屈光状态和 VA 无显著相关性。然而，BI 可能伴随着眼屈光系统发育不平衡。此外，从 BI 的角度来看，主导眼的 SE 倾向于随着数值的增加而变得更负。临床试验注册号：ChiCTR2100045457。
