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咖啡——抗氧化剂的来源与青春之泉。

Coffee as a Source of Antioxidants and an Elixir of Youth.

作者信息

Kobylińska Zofia, Biesiadecki Marek, Kuna Ewelina, Galiniak Sabina, Mołoń Mateusz

机构信息

Faculty of Biology and Nature Protection, Rzeszów University, Zelwerowicza 4, 35-601 Rzeszów, Poland.

Faculty of Medicine, Rzeszów University, Warzywna 1a, 35-310 Rzeszów, Poland.

出版信息

Antioxidants (Basel). 2025 Feb 27;14(3):285. doi: 10.3390/antiox14030285.

DOI:10.3390/antiox14030285
PMID:40227264
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11939571/
Abstract

Coffee is more than a universally loved beverage; it is a complex matrix of bioactive compounds that contribute to its multifaceted health benefits. From its role as a potent source of antioxidants to its potential anti-aging effects, coffee has proven to be a valuable component of a balanced diet. This paper highlights the extensive scientific evidence supporting coffee's ability to combat oxidative stress, enhance cognitive function, and improve metabolic and cardiovascular health. Additionally, its role in modulating key cellular pathways underscores its potential to positively influence aging and longevity. This manuscript emphasizes coffee's broader cultural, economic, and historical significance, illustrating its enduring relevance in contemporary society. Despite minor discrepancies in research findings, the preponderance of evidence underscores coffee's potential as a functional food with profound implications for healthspan and aging. While promising, translating findings to humans requires further clinical research.

摘要

咖啡不仅仅是一种广受欢迎的饮品;它是一种生物活性化合物的复杂组合,这些化合物带来了多方面的健康益处。从其作为强大抗氧化剂来源的作用到潜在的抗衰老效果,咖啡已被证明是均衡饮食中的宝贵成分。本文强调了大量科学证据,这些证据支持咖啡具有对抗氧化应激、增强认知功能以及改善代谢和心血管健康的能力。此外,它在调节关键细胞途径中的作用突出了其对衰老和长寿产生积极影响的潜力。本手稿强调了咖啡更广泛的文化、经济和历史意义,说明了它在当代社会中持久的相关性。尽管研究结果存在一些细微差异,但大量证据强调了咖啡作为一种功能性食品的潜力,这对健康寿命和衰老具有深远影响。虽然前景乐观,但将研究结果应用于人类还需要进一步的临床研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a1a/11939571/84fc70006110/antioxidants-14-00285-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a1a/11939571/84fc70006110/antioxidants-14-00285-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a1a/11939571/84fc70006110/antioxidants-14-00285-g001.jpg

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Coffee Compounds Protection Against Lipotoxicity Is Associated with Lipid Droplet Formation and Antioxidant Response in Primary Rat Hepatocytes.咖啡化合物对脂毒性的保护作用与原代大鼠肝细胞中脂滴形成及抗氧化反应有关。
Antioxidants (Basel). 2025 Jan 31;14(2):175. doi: 10.3390/antiox14020175.
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1-Methylxanthine enhances memory and neurotransmitter levels.1-甲基黄嘌呤可增强记忆力并提高神经递质水平。
PLoS One. 2025 Jan 16;20(1):e0313486. doi: 10.1371/journal.pone.0313486. eCollection 2025.
4
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Cancer. 2025 Jan 15;131(2):e35620. doi: 10.1002/cncr.35620. Epub 2024 Dec 23.
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Anti-aging and immunomodulatory role of caffeine in larvae.咖啡因在幼虫中的抗衰老和免疫调节作用。
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Sci Rep. 2024 Sep 10;14(1):21063. doi: 10.1038/s41598-024-71426-y.
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Diabetes Metab Syndr. 2024 Jul;18(7):103075. doi: 10.1016/j.dsx.2024.103075. Epub 2024 Jul 16.
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