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伴有脑出血的心房黏液瘤。

Atrial myxoma presenting with cerebral haemorrhage.

作者信息

Macaulay V M, Crawford P J, McKeran R O

出版信息

Postgrad Med J. 1985 Apr;61(714):331-2. doi: 10.1136/pgmj.61.714.331.

DOI:10.1136/pgmj.61.714.331
PMID:4022864
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2418233/
Abstract

Emboli from left atrial myxomas are a recognized cause of cerebral ischaemia. The myxomatous embolus may infiltrate the cerebral arterial wall, resulting in aneurysmal dilatation with a risk of rupture. Myxoma-associated cerebral haemorrhage has been described in patients with progressive neurological dysfunction. We report a new presentation. Our patient, a previously healthy 20 year old girl, developed acute intracerebral haemorrhage for which craniotomy was performed. Histology of evacuated haematoma revealed an intravascular fragment of myxoma. Echocardiography demonstrated a left atrial myxoma which later was uneventfully excised. Early diagnosis of embolic cardiac myxoma requires awareness of the diversity of clinical manifestations, and careful histological analysis of surgical specimens.

摘要

左心房黏液瘤的栓子是脑缺血的一个公认病因。黏液瘤栓子可能浸润脑动脉壁,导致动脉瘤样扩张并有破裂风险。黏液瘤相关的脑出血在有进行性神经功能障碍的患者中已有描述。我们报告一种新的表现形式。我们的患者是一名此前健康的20岁女孩,发生急性脑出血并接受了开颅手术。清除的血肿组织学检查显示为黏液瘤的血管内碎片。超声心动图显示左心房黏液瘤,随后顺利切除。栓塞性心脏黏液瘤的早期诊断需要认识到临床表现的多样性,并对手术标本进行仔细的组织学分析。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5d/2418233/ed4f739d02b1/postmedj00110-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5d/2418233/4eb044e779ab/postmedj00110-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5d/2418233/ed4f739d02b1/postmedj00110-0046-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5d/2418233/4eb044e779ab/postmedj00110-0045-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb5d/2418233/ed4f739d02b1/postmedj00110-0046-a.jpg

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引用本文的文献

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Brain embolism secondary to cardiac myxoma in fifteen Chinese patients.15例中国患者继发于心脏黏液瘤的脑栓塞
ScientificWorldJournal. 2014 Mar 9;2014:718246. doi: 10.1155/2014/718246. eCollection 2014.
2
Multiple cerebral aneurysms caused by cardiac myxoma. A case report and present state of knowledge.心脏黏液瘤所致多发性脑动脉瘤。病例报告及知识现状。
Interv Neuroradiol. 2007 Jun;13(2):179-84. doi: 10.1177/159101990701300209. Epub 2007 Sep 13.

本文引用的文献

1
Cardiac myxomas with systemic embolization. Review of the literature and report of a case.伴有全身栓塞的心脏黏液瘤。文献综述及一例病例报告。
Circulation. 1962 Jul;26:99-103. doi: 10.1161/01.cir.26.1.99.
2
Delayed neurologic complications of left atrial myxoma.左心房黏液瘤的迟发性神经并发症
Neurology. 1981 Jan;31(1):8-13. doi: 10.1212/wnl.31.1.8.
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Atrial myxoma: a treatable cause of stroke.心房黏液瘤:一种可治疗的中风病因。
J Neurol Neurosurg Psychiatry. 1969 Apr;32(2):129-33. doi: 10.1136/jnnp.32.2.129.
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Cardiac myxoma. A clinicopathologic and angiographic study.心脏黏液瘤。一项临床病理与血管造影研究。
Arch Neurol. 1970 Dec;23(6):558-67. doi: 10.1001/archneur.1970.00480300080011.
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Left atrial myxoma as a neurological problem: a case report and review.左心房黏液瘤作为一种神经系统问题:病例报告及文献复习
Stroke. 1973 May-Jun;4(3):451-8. doi: 10.1161/01.str.4.3.451.
6
Atrial myxoma with intellectual decline and cerebral growths on CT scan.伴有智力衰退及CT扫描显示脑部有肿物的心房黏液瘤
Ann Neurol. 1979 Apr;5(4):396-400. doi: 10.1002/ana.410050417.