Niu Qian, Jiang Zhiwen, Wang Lifang, Ji Xiang, Baele Guy, Qin Ying, Lin Liyan, Lai Alexander, Chen Ye, Veit Michael, Su Shuo
Department of Laboratory Medicine/Clinical Laboratory Medicine Research Center, West China Hospital, Sichuan University, Chengdu, China.
Engineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Academy for Advanced Interdisciplinary Studies, Nanjing Agricultural University, Nanjing, China.
Nat Commun. 2025 Apr 15;16(1):3558. doi: 10.1038/s41467-025-58882-4.
The natural host for avian influenza virus (AIV) is waterfowl. However, certain subtypes have breached species barriers, causing epizootics in many avian and mammalian species with occasional zoonotic infections in humans. The ongoing spread of highly pathogenic avian influenza (HPAI) A(H5N1) poses a significant and growing public health threat. Here, we discuss recent advances in viral detection and characterization technologies and their integration into the diagnostics and surveillance of AIV within a “One Health” framework.
禽流感病毒（AIV）的天然宿主是水禽。然而，某些亚型突破了物种屏障，在许多禽类和哺乳动物物种中引发了 epizootics，偶尔也会感染人类，导致人畜共患病。高致病性禽流感（HPAI）A（H5N1）的持续传播对公共卫生构成了重大且日益严重的威胁。在此，我们讨论病毒检测和鉴定技术的最新进展，以及它们如何在“同一健康”框架内整合到 AIV 的诊断和监测中。
