Morel C, Ferraina P, Valente A, Cervio R
Acta Gastroenterol Latinoam. 1981;11(1):171-93.
The study of a group of 151 patients confirms the diagnostic value of elevated ACCR in pancreatitis, it was positive in 89.4% of them, of the group, 30 were normal, 19 exhibited acute pancreatitis and 102 had various other pathologies. Serious pancreatitis has shown coincide with a long-lasting rise of ACCR, and its rise in the course of the disease was a sign of a new outburst of progressive necrosis. Total unreliability when abnormal creatinine clearance is present was ascertained. The possible mechanism of increase in ACCR has been considered also in connection with the study of the results obtained on a group of patients exhibiting renal insufficiency, gastrointestinal bleeding, acute colecystitis, vesicular lithiasis and obstructive jaundice.
对151名患者的研究证实了ACCR升高在胰腺炎中的诊断价值,其中89.4%呈阳性。该组中,30人正常,19人患急性胰腺炎,102人有其他各种病症。重症胰腺炎与ACCR的持续升高相符,其在病程中的升高是进行性坏死新发作的迹象。当存在异常肌酐清除率时,可确定其完全不可靠。还结合对一组患有肾功能不全、胃肠道出血、急性胆囊炎、胆囊结石和梗阻性黄疸患者的研究结果,探讨了ACCR升高的可能机制。