Mesias Marta, González-Mulero Lucía, Morales Francisco J, Delgado-Andrade Cristina
Institute of Food Science, Technology and Nutrition (ICTAN-CSIC), José Antonio Novais 6, 28040 Madrid, Spain.
Foods. 2025 Mar 20;14(6):1073. doi: 10.3390/foods14061073.
This study conducted a total acrylamide exposure assessment through the daily diet in two Spanish senior centers using the duplicate diet method. Among foods regulated in Europe, only instant coffee provided at senior center 1 (2831 µg/kg) exceeded the benchmark value of 850 µg/kg. The primary contributors to acrylamide intake were French fries (27.3 µg/serving) and Spanish omelet (21.6 µg/serving), followed by stews, soups, and creams (16.1-5.8 µg/serving). Total acrylamide exposure was estimated under lower bound (LB) and upper bound (UB) scenarios, being 0.36-0.40 and 0.48-0.54 µg/kg bw/day, respectively. In the LB scenario, cereal-based products were the largest contributors (≤90.4%), whereas in the UB scenario, other foods/meals, including stews and vegetal dishes, became the main contributors (≤83.4%). The margin of exposure (MOE) for neoplastic effects ranged between 314 and 474, indicating a potential health risk for consumers. These findings emphasize the need to integrate nutritional and food safety considerations when designing diets for elderly populations.
本研究采用双份膳食法，通过西班牙两个老年中心的日常饮食对丙烯酰胺的总暴露量进行了评估。在欧洲规定的食品中，只有老年中心1提供的速溶咖啡（2831微克/千克）超过了850微克/千克的基准值。丙烯酰胺摄入量的主要来源是炸薯条（27.3微克/份）和西班牙煎蛋饼（21.6微克/份），其次是炖菜、汤和奶油（16.1 - 5.8微克/份）。在下限（LB）和上限（UB）两种情况下估计了丙烯酰胺的总暴露量，分别为0.36 - 0.40微克/千克体重/天和0.48 - 0.54微克/千克体重/天。在下限情况下，谷物类产品是最大的贡献者（≤90.4%），而在上限情况下，包括炖菜和蔬菜菜肴在内的其他食品/餐食成为主要贡献者（≤83.4%）。肿瘤效应的暴露边际（MOE）在314至474之间，表明消费者存在潜在健康风险。这些发现强调了在为老年人群设计饮食时整合营养和食品安全考虑因素的必要性。
