Canton J H, Slooff W, Kool H J, Struys J, Pouw T J, Wegman R C, Piet G J
Regul Toxicol Pharmacol. 1985 Jun;5(2):123-31. doi: 10.1016/0273-2300(85)90026-1.
The evaluation of the ecotoxicity of chemical compounds is often hampered by the scarcity of the literature data on toxicity, biodegradability, and accumulation. In this study additional data on 16 Cl/N-containing organic compounds were gathered by laboratory experiments. For assignment to so-called gray or black lists, two different classification schemes were used. According to both schemes 3-nitrotoluene, 1,2- and 1,3-dichlorobenzene, the 1-chloro-nitrobenzenes, 2,3-dichloronitrobenzene, 2-chloroaniline, and 2-chloro-4-nitroaniline were marked as black list substances, primarily based on poor biodegradability; 2- and 4-nitrotoluene, nitrobenzene, and 2-methoxyaniline were classified as gray list substances. For 3- and 4-methoxyaniline and 1,4-dichlorobenzene no agreement in classification was obtained. Additionally, water quality criteria are proposed for 2-, 3-, and 4-nitrotoluene and nitrobenzene, based on long-term toxicity data: respectively 0.3, 0.2, 0.4, and 1.0 mg/liter.
化合物生态毒性的评估常常因毒性、生物降解性和累积方面的文献数据匮乏而受阻。在本研究中，通过实验室实验收集了16种含氯/氮有机化合物的额外数据。为了将其归入所谓的灰色或黑色清单，使用了两种不同的分类方案。根据这两种方案，3-硝基甲苯、1,2-和1,3-二氯苯、氯代硝基苯、2,3-二氯硝基苯、2-氯苯胺和2-氯-4-硝基苯胺主要基于生物降解性差被列为黑色清单物质；2-和4-硝基甲苯、硝基苯和2-甲氧基苯胺被归类为灰色清单物质。对于3-和4-甲氧基苯胺以及1,4-二氯苯，在分类上未达成一致。此外，基于长期毒性数据，针对2-、3-和4-硝基甲苯以及硝基苯提出了水质标准：分别为0.3、0.2、0.4和1.0毫克/升。
