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一名无症状幼儿心脏炎性肌纤维母细胞瘤致肺动脉梗阻的意外发现

Unexpected Finding of an Inflammatory Myofibroblastic Tumor of the Heart Causing Pulmonary Artery Obstruction in an Asymptomatic Toddler.

作者信息

Morel Sara B A, Fadel Elie, Gao Sophie W, Dal Soglio Dorothée, Bernier Pierre-Luc

机构信息

Division of Cardiac Surgery, McGill University, Montreal, Quebec, Canada.

Division of Cardiac Surgery, McMaster University, Hamilton, Ontario, Canada.

出版信息

World J Pediatr Congenit Heart Surg. 2025 Sep;16(5):685-687. doi: 10.1177/21501351251322154. Epub 2025 Apr 15.

DOI:10.1177/21501351251322154
PMID:40233109
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12326023/
Abstract

Inflammatory myofibroblastic tumor (IMT) of the heart is a very rare tumor, constituting less than 5% of primary heart tumors. This case report describes the unexpected finding of IMT of the heart causing pulmonary artery obstruction in an asymptomatic toddler.

摘要

心脏炎性肌纤维母细胞瘤（IMT）是一种非常罕见的肿瘤，占原发性心脏肿瘤的比例不到5%。本病例报告描述了一名无症状幼儿中意外发现的心脏IMT导致肺动脉梗阻的情况。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1fd/12326023/64d1fe7c1839/10.1177_21501351251322154-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1fd/12326023/f169cfe75c59/10.1177_21501351251322154-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1fd/12326023/5822246b3b42/10.1177_21501351251322154-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1fd/12326023/6f8df32d0cb6/10.1177_21501351251322154-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1fd/12326023/64d1fe7c1839/10.1177_21501351251322154-fig4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1fd/12326023/f169cfe75c59/10.1177_21501351251322154-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1fd/12326023/5822246b3b42/10.1177_21501351251322154-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1fd/12326023/6f8df32d0cb6/10.1177_21501351251322154-fig3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b1fd/12326023/64d1fe7c1839/10.1177_21501351251322154-fig4.jpg

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本文引用的文献

1
A Pediatric Primary Cardiac Spindle Cell Neoplasm With a Rare PDGFRA::USP8 Gene Fusion: A Case Report.儿童原发性心脏梭形细胞肿瘤伴罕见 PDGFRA::USP8 基因融合：病例报告。
Pediatr Dev Pathol. 2024 Jul-Aug;27(4):335-339. doi: 10.1177/10935266231221903. Epub 2024 Feb 24.
2
Expanding the spectrum of tyrosine kinase fusions in calcified chondroid mesenchymal neoplasms: Identification of a novel PDGFRA::USP8 gene fusion.扩展钙化软骨性间叶性肿瘤中酪氨酸激酶融合的谱：鉴定一种新型 PDGFRA::USP8 基因融合。
Genes Chromosomes Cancer. 2024 Jan;63(1):e23197. doi: 10.1002/gcc.23197. Epub 2023 Aug 29.
3
Inflammatory myofibroblastic tumor of the heart: A brief overview.
心脏炎性肌纤维母细胞瘤：简要概述
Rev Port Cardiol. 2023 Feb;42(2):171-172. doi: 10.1016/j.repc.2022.12.010. Epub 2022 Dec 20.
4
Cardiac Inflammatory Myofibroblastic Tumor Causing Pulmonary Artery Obstruction: A Rare Case Report.导致肺动脉梗阻的心脏炎性肌纤维母细胞瘤：1例罕见病例报告
J Pediatr Hematol Oncol. 2021 Oct 1;43(7):e903-e906. doi: 10.1097/MPH.0000000000002000.
5
Cardiac Tumors in Pediatric Patients: A Systematic Review.小儿心脏肿瘤：一项系统综述
World J Pediatr Congenit Heart Surg. 2017 Sep;8(5):624-632. doi: 10.1177/2150135117723904.
6
Inflammatory Myofibroblastic Tumor of the Heart in the Infant: Review of the Literature.婴儿心脏炎性肌纤维母细胞瘤：文献综述
J Pediatr Hematol Oncol. 2016 Nov;38(8):e298-e302. doi: 10.1097/MPH.0000000000000558.
7
Inflammatory myofibroblastic tumor of the heart.心脏炎性肌纤维母细胞瘤
Heart Vessels. 2014 Jan;29(1):123-8. doi: 10.1007/s00380-013-0344-z. Epub 2013 Apr 11.
8
Fibroma and inflammatory myofibroblastic tumor of the heart.心脏纤维瘤和炎性肌成纤维细胞瘤
Ann Diagn Pathol. 2001 Dec;5(6):335-42. doi: 10.1053/adpa.2001.29340.