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小儿心脏肿瘤:一项系统综述

Cardiac Tumors in Pediatric Patients: A Systematic Review.

作者信息

Tzani Aspasia, Doulamis Ilias P, Mylonas Konstantinos S, Avgerinos Dimitrios V, Nasioudis Dimitrios

机构信息

1 Surgery Working Group, Society of Junior Doctors, Athens, Greece.

2 Division of Pediatric Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.

出版信息

World J Pediatr Congenit Heart Surg. 2017 Sep;8(5):624-632. doi: 10.1177/2150135117723904.

Abstract

This systematic review sought to investigate the current evidence regarding surgical management of primary cardiac tumors in children and adolescents. Twenty-eight studies were deemed eligible, reporting on 745 pediatric patients. Rhabdomyoma was the most prevalent histologic type and echocardiography was the most common diagnostic tool. Cumulative 30-day mortality rate was 6.7%. Rhabdomyomas and teratomas had the highest 30-day mortality. The higher percentage of tumor relapse was noted for myxoma and teratoma. Although cardiac tumors are rare, their atypical clinical presentation, potential for recurrence, and the poor prognosis associated with recurrence elucidate the need for reliable diagnostic and therapeutic management.

摘要

本系统评价旨在调查目前有关儿童和青少年原发性心脏肿瘤外科治疗的证据。28项研究被认为符合要求,报告了745例儿科患者。横纹肌瘤是最常见的组织学类型,超声心动图是最常用的诊断工具。30天累积死亡率为6.7%。横纹肌瘤和畸胎瘤的30天死亡率最高。黏液瘤和畸胎瘤的肿瘤复发率较高。虽然心脏肿瘤罕见,但其非典型临床表现、复发可能性以及与复发相关的不良预后表明需要可靠的诊断和治疗管理。

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