[球后视神经炎作为多发性硬化的首发症状。一项前瞻性研究的结果]

[Retrobulbar optic neuritis as an initial symptom of multiple sclerosis. Results of a prospective study].

作者信息

Mapelli G, De Palma P, Fini M, Pavoni M, Franco F, Pirazzoli G

出版信息

Riv Neurol. 1985 Jan-Feb;55(1):53-77.

Abstract

40 patients with idiopathic optic neuritis (ON) between 1st January 1967 and 31st December 1977 have been checked again from oculistic and neurological point of view between 1st January and 31st March 1983. 10 of 40 examined patients (25%) are found suffering from multiple sclerosis (MS) at the time of check up. Our research points out that idiopathic ON evolutive risk towards MS is greater in females, in people between 20 and 40 years old, in people with one or more relapses as well as in people with neurological microsymptoms at the time of ON.

摘要

1967年1月1日至1977年12月31日期间的40例特发性视神经炎（ON）患者，于1983年1月1日至3月31日期间再次接受了眼科和神经科检查。在40例接受检查的患者中，有10例（25%）在检查时被发现患有多发性硬化症（MS）。我们的研究指出，特发性ON向MS发展的风险在女性、20至40岁的人群、有一次或多次复发的人群以及ON发作时有神经微症状的人群中更高。