Radhakrishna Kishen, Holland Jessica, O'Keeffe Fiadhnait, Gaynor Keith, Kinsella Justin, Bramham Jessica
Neurology, St. Vincent's University Hospital, Dublin, IRL.
Neuropsychology, St. Vincent's University Hospital, Dublin, IRL.
Cureus. 2025 Apr 15;17(4):e82311. doi: 10.7759/cureus.82311. eCollection 2025 Apr.
Aim To determine the sensitivity and specificity of the psychometric measures of the A-B Neuropsychological Assessment Schedule (ABNAS) to aid screening of long COVID (LC). Methods The participants (N=235) were recruited from an online study of cognitive and psychological consequences of LC, involving individuals attending an LC service in an acute tertiary university hospital and a comparison sample of community controls.The ABNAS for LC, a patient-perceived assessment scale in relation to the challenges they had encountered from LC, was used to identify the specific psychometric measures implicated in LC. Results The optimal cut-off value for total ABNAS scores and its psychometric subsets were obtained from receiver operating characteristic (ROC) curves. The sensitivity of the total ABNAS score of ≥21.5 was 81.6% for LC, taken as a post-COVID functional status (PCFS)grade of ≥ 2 as true positives, with a specificity = 72.3%. The specificity of the ABNAS fatigue subscale score of ≥ 8.5 for LC was 87.2%, while its sensitivity was 66.7%. The sensitivity of the ABNAS mental slowing subscale score of ≥ 4.5 was 82.8%, and the specificity was 70.3%. Conclusion Total ABNAS scores and their psychometric subsets (fatigue and mental slowing) are sensitive and specific for LC.
确定A - B神经心理学评估量表（ABNAS）心理测量指标对辅助筛查长期新冠（LC）的敏感性和特异性。方法：参与者（N = 235）来自一项关于LC认知和心理后果的在线研究，包括在一家急性三级大学医院的LC服务中心就诊的个体以及社区对照的比较样本。用于评估患者对LC所面临挑战感受的LC - ABNAS量表，被用来确定与LC相关的特定心理测量指标。结果：通过受试者工作特征（ROC）曲线得出ABNAS总分及其心理测量子集的最佳截断值。以新冠后功能状态（PCFS）等级≥2为真阳性，ABNAS总分≥21.5对LC的敏感性为81.6%，特异性为72.3%。ABNAS疲劳子量表得分≥8.5对LC的特异性为87.2%，而其敏感性为66.7%。ABNAS思维迟缓子量表得分≥4.5的敏感性为82.8%，特异性为70.3%。结论：ABNAS总分及其心理测量子集（疲劳和思维迟缓）对LC具有敏感性和特异性。
