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孤立性鞍上脊索瘤酷似垂体腺瘤:1例报告

Isolated Suprasellar Chordoma Mimicking Pituitary Adenoma: A Case Report.

作者信息

Al-Quwayee Mohammed K, Albadr Fahad, Almasoud Rayan N, Alghamdi Nawaf, Alhathloul Zeyad Abdulrahman, Alquhidan Mohamed

机构信息

Neuroradiology, King Saud University Medical City, Riyadh, SAU.

Radiology and Medical Imaging, King Saud University Medical City, Riyadh, SAU.

出版信息

Cureus. 2025 Mar 16;17(3):e80647. doi: 10.7759/cureus.80647. eCollection 2025 Mar.

DOI:10.7759/cureus.80647
PMID:40236339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11998626/
Abstract

Chordomas are uncommon neoplasms predominantly observed in adult males, typically middle-aged. These tumors present with diverse clinical features, including headaches, cranial neuropathies, and cerebrospinal fluid leakage. Surgical intervention is often complex due to tumor location or postresection reconstruction requirements, necessitating a multidisciplinary approach for optimal management. The report describes an atypical case of a 20-year-old female patient presenting with persistent headaches and visual disturbances. Magnetic resonance imaging (MRI) revealed a large sellar/suprasellar mass initially suggestive of a pituitary adenoma. Following surgical excision, histopathological analysis confirmed a chordoma. This report emphasizes the diagnostic and therapeutic challenges of suprasellar chordomas, which may radiologically mimic common sellar lesions. The case underscores the importance of including chordoma in the differential diagnosis of sellar/suprasellar masses, especially in younger patients with visual impairment and headache.

摘要

脊索瘤是一种罕见的肿瘤,主要见于成年男性,通常为中年。这些肿瘤具有多种临床特征,包括头痛、颅神经病变和脑脊液漏。由于肿瘤位置或切除后重建需求,手术干预往往很复杂,因此需要多学科方法进行最佳管理。该报告描述了一名20岁女性患者的非典型病例,该患者表现为持续性头痛和视力障碍。磁共振成像(MRI)显示鞍区/鞍上有一个大肿块,最初提示垂体腺瘤。手术切除后,组织病理学分析证实为脊索瘤。本报告强调了鞍上脊索瘤的诊断和治疗挑战,其在放射学上可能与常见的鞍区病变相似。该病例强调了在鞍区/鞍上肿块的鉴别诊断中纳入脊索瘤的重要性,尤其是在有视力障碍和头痛的年轻患者中。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9585/11998626/1c4bba2fe7b9/cureus-0017-00000080647-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9585/11998626/7f81677ee96a/cureus-0017-00000080647-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9585/11998626/0c0d4a62ed7e/cureus-0017-00000080647-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9585/11998626/d2b9303de952/cureus-0017-00000080647-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9585/11998626/1c4bba2fe7b9/cureus-0017-00000080647-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9585/11998626/7f81677ee96a/cureus-0017-00000080647-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9585/11998626/0c0d4a62ed7e/cureus-0017-00000080647-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9585/11998626/d2b9303de952/cureus-0017-00000080647-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9585/11998626/1c4bba2fe7b9/cureus-0017-00000080647-i04.jpg

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