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一名年轻男性患者斜坡脊索瘤罕见病例的诊断与治疗

Diagnosis and management of a rare case of clival chordoma in a young male patient.

作者信息

Masino Federica, Montatore Manuela, Balbino Marina, Andrea D'Arma Giuseppe Maria, Muscatella Gianmichele, Gifuni Rossella, Guglielmi Giuseppe

机构信息

Department of Clinical and Experimental Medicine, Foggia University School of Medicine, Viale L. Pinto 1, 71121, Foggia (FG), Italy.

Radiology Unit, "Dimiccoli" Hospital, Viale Ippocrate 15, 70051, Barletta (BT), Italy.

出版信息

Radiol Case Rep. 2024 Jun 15;19(9):3683-3687. doi: 10.1016/j.radcr.2024.05.064. eCollection 2024 Sep.

DOI:10.1016/j.radcr.2024.05.064
PMID:38983299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11228638/
Abstract

Chordomas are uncommon bone slow-growing tumors developing from remnants of the notochord. They are typically seen in adults, and rarely in children. We present the case of a 16-year-old male patient with a clival chordoma, presenting with progressive headache and diplopia. In this case report we aim to provide an educational explanation of the radiological findings, diagnostic challenges, and therapeutic and management strategies.

摘要

脊索瘤是一种罕见的起源于脊索残余组织的骨骼缓慢生长肿瘤。它们通常见于成年人，儿童罕见。我们报告一例16岁男性斜坡脊索瘤患者，表现为进行性头痛和复视。在本病例报告中，我们旨在对影像学表现、诊断挑战以及治疗和管理策略进行有教育意义的解释。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/f5f118527c8b/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/0d2fee93361e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/8c8195f99650/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/77ba34de4d31/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/e9100a00c06b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/c094ccc742f5/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/da77565e4fe2/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/f5f118527c8b/gr7.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/0d2fee93361e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/8c8195f99650/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/77ba34de4d31/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/e9100a00c06b/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/c094ccc742f5/gr5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/da77565e4fe2/gr6.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5397/11228638/f5f118527c8b/gr7.jpg

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Int J Surg Case Rep. 2024 Mar;116:109393. doi: 10.1016/j.ijscr.2024.109393. Epub 2024 Feb 15.
2
Chronic cerebrospinal fluid rhinorrhea as an initial presentation of chordoma: illustrative case.慢性脑脊液鼻漏作为脊索瘤的首发表现：病例报告
J Neurosurg Case Lessons. 2023 Apr 3;5(14). doi: 10.3171/CASE2347.
3
Isolated Third Nerve Palsy as the Initial Manifestation of a Large Clival Chordoma.
孤立性动眼神经麻痹作为巨大斜坡脊索瘤的首发表现
J Neuroophthalmol. 2024 Mar 1;44(1):e117-e119. doi: 10.1097/WNO.0000000000001764. Epub 2022 Dec 23.
4
MRI enhancement patterns in 28 cases of clival chordomas.28 例斜坡脊索瘤的 MRI 增强模式。
J Clin Neurosci. 2022 May;99:117-122. doi: 10.1016/j.jocn.2022.02.037. Epub 2022 Mar 9.
5
Clival Chordoma: A Rare Finding in Children.斜坡脊索瘤：儿童中的罕见发现。
J Belg Soc Radiol. 2021 Feb 22;105(1):10. doi: 10.5334/jbsr.2334.
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Chordoma: F-FDG PET/CT and MRI imaging features.脊索瘤： F-FDG PET/CT 和 MRI 成像特征。
Skeletal Radiol. 2021 Aug;50(8):1657-1666. doi: 10.1007/s00256-021-03723-w. Epub 2021 Feb 1.
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Clival chordoma in a young male patient: a case report.年轻男性患者的鞍结节脊索瘤：病例报告。
Pan Afr Med J. 2020 Sep 15;37:59. doi: 10.11604/pamj.2020.37.59.24836. eCollection 2020.
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Korean J Fam Med. 2020 Nov;41(6):427-430. doi: 10.4082/kjfm.19.0004. Epub 2020 May 22.
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State-of-the-Art Imaging in Human Chordoma of the Skull Base.颅底脊索瘤的最新成像技术
Curr Radiol Rep. 2018;6(5):16. doi: 10.1007/s40134-018-0275-7. Epub 2018 Apr 3.