Ghiggia Ada, Tesio Valentina, Colonna Fabrizio, Fusaro Enrico, Geminiani Giuliano Carlo, Castelli Lorys
Department of Life Sciences, University of Trieste, 34128 Trieste, Italy.
Department of Psychology, University of Turin, 10124 Turin, Italy.
Int J Environ Res Public Health. 2025 Mar 2;22(3):366. doi: 10.3390/ijerph22030366.
The study analyzed the role of traumatic experiences and psychosomatic components as potential predictors of the likelihood of chronic pain patients having or not having fibromyalgia.
We examined the role of stressful life events (Traumatic Experiences Checklist), psychosomatic syndromes (Toronto Alexithymia Scale and Diagnostic Criteria for Psychosomatic Research), pain, and psychological distress (Beck Depression Inventory-II and State-Trait Anxiety Inventory) in 104 patients with fibromyalgia compared with a sample of 104 patients with rheumatoid arthritis.
Patients with fibromyalgia reported significantly more traumatic events, a higher prevalence of psychosomatic syndromes, and higher levels of pain, anxiety and depressive symptoms compared with patients with rheumatoid arthritis (all < 0.01). Hierarchical binary logistic regression with group membership as the dependent variable showed that somatization syndromes (OR = 3.67), pain (OR = 1.56), and childhood trauma (OR = 1.11) were statistically significant predictors of group belonging, and the model explained 67% of the variance in diagnosis [χ(9) = 143.66, < 0.001].
These results highlighted that patients with fibromyalgia are characterized primarily by marked somatization and a high prevalence of early stressful life events compared with patients with rheumatoid arthritis, a primarily nociceptive chronic pain condition. A better knowledge of these mechanisms could allow clinicians to develop tailored interventions that take greater account of the psychological dimension of the disease.
本研究分析了创伤经历和心身因素作为慢性疼痛患者是否患有纤维肌痛可能性的潜在预测因素的作用。
我们在104例纤维肌痛患者中研究了应激性生活事件(创伤经历清单)、心身综合征(多伦多述情障碍量表和心身研究诊断标准)、疼痛和心理困扰(贝克抑郁量表第二版和状态-特质焦虑量表)的作用,并与104例类风湿性关节炎患者样本进行了比较。
与类风湿性关节炎患者相比,纤维肌痛患者报告的创伤事件显著更多,心身综合征患病率更高,疼痛、焦虑和抑郁症状水平更高(均P<0.01)。以分组作为因变量的分层二元逻辑回归显示,躯体化综合征(优势比=3.67)、疼痛(优势比=1.56)和童年创伤(优势比=1.11)是分组的统计学显著预测因素,该模型解释了诊断差异的67%[χ(9)=143.66,P<0.001]。
这些结果突出表明,与类风湿性关节炎患者(一种主要为伤害性感受的慢性疼痛疾病)相比,纤维肌痛患者的主要特征是明显的躯体化和早期应激性生活事件的高患病率。更好地了解这些机制可以使临床医生制定更具针对性的干预措施,更多地考虑疾病的心理维度。