Mokhtar Murnizar, Zaki Nor Azian Mohd, Ibrahim Nurul Huda
Centre for Nutrition Epidemiology Research, Institute for Public Health, National Institute of Health, Ministry of Health of Malaysia, Shah Alam, Malaysia.
PLoS One. 2025 Apr 16;20(4):e0320993. doi: 10.1371/journal.pone.0320993. eCollection 2025.
Impaired fasting glucose (IFG) is a condition when a person's blood glucose level is above the normal range, but below the diagnostic cut-off for a formal diagnosis of diabetes mellitus. The objective of this study was to determine the prevalence of IFG among adults aged 18 years and older in Malaysia and its' associated factors. Data were obtained as part of the National Health and Morbidity Survey (NHMS) 2019 [1]. It was a community-based, cross-sectional study that was conducted among a targeted population in both urban and rural areas in all 13 states and 3 federal territories in Malaysia, using a two stage stratified random sampling method. Adults aged 18 years and older with fasting capillary blood glucose (FBG) readings of ≤ 6.9 mmol/L were selected, except those known to have diabetes. IFG was defined according to World Health Organization (WHO) criteria as FBG between 6.1 and 6.9 mmol/L. The data were analyzed using SPSS Version 28.0. A total of 6183 respondents - 2842 men and 3341 women participated in this study. The overall prevalence of IFG was 22.6% (95% CI: 20.4, 24.9). Respondents aged 60 years and older had the highest percentage of IFG at about 30.2% (95% CI: 26.4, 34.4), followed by respondents with hypercholesterolemia at 29.2% (95% CI: 25.2, 33.6) and respondents with hypertension at 27.7% (95% CI: 24.3, 31.4). Multivariate analysis revealed that age of 60 years and above (aOR 1.51, 95% CI: 1.01, 2.06) and marriage (aOR 1.46, 95% CI: 1.16, 1.84) were significantly associated with IFG. The prevalence of IFG among Malaysian adults according to data obtained in 2019 was 22.6%, with an age of 60 and above and married being the associated factors. Policies need to be tailored for more vigorous screening among this group for prompt diagnosis and treatment to prevent complications.
空腹血糖受损（IFG）是指一个人的血糖水平高于正常范围，但低于糖尿病正式诊断的诊断临界值的一种情况。本研究的目的是确定马来西亚18岁及以上成年人中IFG的患病率及其相关因素。数据是作为2019年全国健康与发病率调查（NHMS）的一部分获得的[1]。这是一项基于社区的横断面研究，采用两阶段分层随机抽样方法，在马来西亚13个州和3个联邦直辖区的城乡目标人群中进行。选取空腹毛细血管血糖（FBG）读数≤6.9 mmol/L的18岁及以上成年人，但已知患有糖尿病的除外。根据世界卫生组织（WHO）标准，IFG定义为FBG在6.1至6.9 mmol/L之间。数据使用SPSS 28.0版进行分析。共有6183名受访者——2842名男性和3341名女性参与了本研究。IFG的总体患病率为22.6%（95%CI：20.4，24.9）。60岁及以上的受访者中IFG的百分比最高，约为30.2%（95%CI：26.4，34.4），其次是高胆固醇血症受访者，为29.2%（95%CI：25.2，33.6），高血压受访者为27.7%（95%CI：24.3，31.4）。多变量分析显示，60岁及以上（调整后比值比1.51，95%CI：1.01，2.06）和婚姻状况（调整后比值比1.46，9%CI：1.16，1.84）与IFG显著相关。根据2019年获得的数据，马来西亚成年人中IFG的患病率为22.6%，60岁及以上和已婚是相关因素。需要制定政策，对该群体进行更积极的筛查，以便及时诊断和治疗，预防并发症。
